2007
Identifying Heart Failure Patients at High Risk for Near-Term Cardiovascular Events With Serial Health Status Assessments
Kosiborod M, Soto GE, Jones PG, Krumholz HM, Weintraub WS, Deedwania P, Spertus JA. Identifying Heart Failure Patients at High Risk for Near-Term Cardiovascular Events With Serial Health Status Assessments. Circulation 2007, 115: 1975-1981. PMID: 17420346, DOI: 10.1161/circulationaha.106.670901.Peer-Reviewed Original ResearchConceptsKansas City Cardiomyopathy QuestionnaireHeart failure outpatientsHealth status assessmentCause mortalityCardiovascular mortalityKaplan-Meier survival analysisHigh-risk patientsHeart failure patientsAcute myocardial infarctionProportional hazards modelIntensity of treatmentStatus assessmentKCCQ scoresCardiovascular deathCardiovascular eventsClinical deteriorationMultivariable adjustmentFailure patientsHeart failureOutpatient visitsMyocardial infarctionHigh riskHospitalizationPatientsCombined outcome
2006
Difficulty Taking Medications, Depression, and Health Status in Heart Failure Patients
Morgan AL, Masoudi FA, Havranek EP, Jones PG, Peterson PN, Krumholz HM, Spertus JA, Rumsfeld JS, Consortium F. Difficulty Taking Medications, Depression, and Health Status in Heart Failure Patients. Journal Of Cardiac Failure 2006, 12: 54-60. PMID: 16500581, DOI: 10.1016/j.cardfail.2005.08.004.Peer-Reviewed Original ResearchConceptsKansas City Cardiomyopathy QuestionnaireHeart failure outpatientsWorse health statusHealth statusDepressive symptomsMedication nonadherenceLeft ventricular ejection fractionPatient-reported difficultyHeart failure populationHeart failure patientsVentricular ejection fractionCross-sectional associationsMore depressive symptomsCoexistent depressionTaking MedicationsFailure patientsClinical factorsEjection fractionMedication adherenceDepression treatmentFailure populationMedical historyClinical evaluationMultivariable regressionMedicationsHealth Status Identifies Heart Failure Outpatients at Risk for Hospitalization or Death
Heidenreich PA, Spertus JA, Jones PG, Weintraub WS, Rumsfeld JS, Rathore SS, Peterson ED, Masoudi FA, Krumholz HM, Havranek EP, Conard MW, Williams RE, Consortium C. Health Status Identifies Heart Failure Outpatients at Risk for Hospitalization or Death. Journal Of The American College Of Cardiology 2006, 47: 752-756. PMID: 16487840, DOI: 10.1016/j.jacc.2005.11.021.Peer-Reviewed Original ResearchConceptsKansas City Cardiomyopathy QuestionnaireB-type natriuretic peptideKCCQ summary scoreHeart failureKCCQ scoresHealth status measuresClinical conditionsNew York Heart Association functional class IVSummary scoresStatus measuresFunctional class IVIschemic HF etiologyLower KCCQ scoresSequential multivariable modelsBaseline patient characteristicsHeart failure outpatientsPatient's clinical conditionProportional hazards regressionBNP levelsHF etiologyHF hospitalizationHF admissionsHF patientsPatient characteristicsWalk distance