2018
Implications of coronary artery calcium testing on risk stratification for lipid-lowering therapy according to the 2016 European Society of Cardiology recommendations: The MESA study
Bittencourt MS, Blankstein R, Blaha MJ, Sandfort V, Agatston AS, Budoff MJ, Blumenthal RS, Krumholz HM, Nasir K. Implications of coronary artery calcium testing on risk stratification for lipid-lowering therapy according to the 2016 European Society of Cardiology recommendations: The MESA study. European Journal Of Preventive Cardiology 2018, 25: 1887-1898. PMID: 30043629, DOI: 10.1177/2047487318788930.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBiomarkersClinical Decision-MakingCoronary AngiographyCoronary Artery DiseaseDyslipidemiasFemaleHumansHypolipidemic AgentsIncidenceLipidsMaleMiddle AgedPractice Guidelines as TopicPredictive Value of TestsPrognosisProspective StudiesRisk AssessmentRisk FactorsUnited StatesVascular CalcificationConceptsLipid-lowering treatmentCoronary artery calciumLipid-lowering therapyArtery calciumHigher cardiovascular mortalityCardiovascular mortalityUncontrolled groupCoronary Artery Calcium TestingCoronary heart disease eventsEuropean SocietyHeart disease eventsCardiovascular mortality ratesCardiovascular risk assessmentLow-risk groupCardiology recommendationsCardiology guidelinesCardiovascular riskESC recommendationsRisk stratificationMESA participantsCalcium testingRisk groupsGroup 31Lower incidenceMESA study
2015
Implications of Coronary Artery Calcium Testing Among Statin Candidates According to American College of Cardiology/American Heart Association Cholesterol Management Guidelines MESA (Multi-Ethnic Study of Atherosclerosis)
Nasir K, Bittencourt MS, Blaha MJ, Blankstein R, Agatson AS, Rivera JJ, Miedema MD, Sibley CT, Shaw LJ, Blumenthal RS, Budoff MJ, Krumholz HM. Implications of Coronary Artery Calcium Testing Among Statin Candidates According to American College of Cardiology/American Heart Association Cholesterol Management Guidelines MESA (Multi-Ethnic Study of Atherosclerosis). Journal Of The American College Of Cardiology 2015, 66: 1657-1668. PMID: 26449135, DOI: 10.1016/j.jacc.2015.07.066.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAmerican Heart AssociationAtherosclerosisCalciumCoronary AngiographyCoronary Artery DiseaseCoronary VesselsEthnicityFemaleFollow-Up StudiesGuideline AdherenceHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedProspective StudiesRisk AssessmentRisk FactorsUnited StatesConceptsCoronary artery calciumASCVD event ratesYears of ageStatin therapyAmerican CollegeAbsence of CACHard coronary heart disease eventsNew ACC/AHA guidelinesCoronary Artery Calcium TestingACC/AHA guidelinesAtherosclerotic cardiovascular disease riskCoronary heart disease eventsLow-density lipoprotein levelsEvent ratesCholesterol management guidelinesHigh-intensity statinsHeart disease eventsLipid-lowering medicationsModerate-intensity statinsCardiovascular disease riskLow-density lipoproteinStatin candidatesASCVD riskAHA guidelinesArtery calcium
2013
Impact of coronary artery calcium on coronary heart disease events in individuals at the extremes of traditional risk factor burden: the Multi-Ethnic Study of Atherosclerosis
Silverman MG, Blaha MJ, Krumholz HM, Budoff MJ, Blankstein R, Sibley CT, Agatston A, Blumenthal RS, Nasir K. Impact of coronary artery calcium on coronary heart disease events in individuals at the extremes of traditional risk factor burden: the Multi-Ethnic Study of Atherosclerosis. European Heart Journal 2013, 35: 2232-2241. PMID: 24366919, PMCID: PMC4150068, DOI: 10.1093/eurheartj/eht508.Peer-Reviewed Original ResearchConceptsCoronary artery calciumCoronary heart disease eventsRisk factor burdenHeart disease eventsMulti-Ethnic StudyCAC 0Artery calciumRF burdenEvent ratesDisease eventsAbsence of CACDistribution of CACTraditional risk factor burdenCHD event ratesElevated event rateHigh CAC burdenFramingham risk scoreLow HDL cholesterolLow event ratesCAC burdenCHD eventsCAC scoreHDL cholesterolLDL cholesterolCigarette smoking
2001
An Evidence-Based Assessment of Federal Guidelines for Overweight and Obesity as They Apply to Elderly Persons
Heiat A, Vaccarino V, Krumholz HM. An Evidence-Based Assessment of Federal Guidelines for Overweight and Obesity as They Apply to Elderly Persons. JAMA Internal Medicine 2001, 161: 1194-1203. PMID: 11343442, DOI: 10.1001/archinte.161.9.1194.Peer-Reviewed Original ResearchConceptsCardiovascular mortalityElderly personsCause mortalityMortality riskCoronary heart disease eventsIdeal weightUS clinical guidelinesHeart disease eventsSignificant prognostic factorsTreatment of overweightBaseline health statusExcess mortality riskRelative mortality riskBody mass indexMiddle-aged populationHigher BMI valuesAdditional pertinent articlesEnglish-language studiesSpecific age groupsPrognostic factorsMass indexSignificant positive associationHealthy weightPrognostic importanceClinical guidelines