2022
Characterization of multi-domain postoperative recovery trajectories after cardiac surgery using a digital platform
Mori M, Dhruva S, Geirsson A, Krumholz H. Characterization of multi-domain postoperative recovery trajectories after cardiac surgery using a digital platform. Npj Digital Medicine 2022, 5: 192. PMID: 36564550, PMCID: PMC9789027, DOI: 10.1038/s41746-022-00736-0.Peer-Reviewed Original ResearchPatient-reported outcome measuresCardiac surgeryProspective cohort studyPROM data collectionPostoperative complicationsCohort studyPostoperative recoveryTertiary centerPatients' perceptionsOutcome measuresClinical practicePatientsSurgeryRecovery progressionRecovery trajectoriesTrajectory membershipComplicationsOverall recoveryDaysAnxiety trajectoriesRecoveryProgressionCareInstitutional Variation in 30‐Day Complications Following Catheter Ablation of Atrial Fibrillation
Ngo L, Ali A, Ganesan A, Woodman R, Krumholz HM, Adams R, Ranasinghe I. Institutional Variation in 30‐Day Complications Following Catheter Ablation of Atrial Fibrillation. Journal Of The American Heart Association 2022, 11: e022009. PMID: 35156395, PMCID: PMC9245833, DOI: 10.1161/jaha.121.022009.Peer-Reviewed Original ResearchConceptsProcedure-related complicationsComplication rateAF ablationAtrial fibrillationCatheter ablationStroke/transient ischemic attackCare qualityTransient ischemic attackRisk of complicationsIschemic attackHospital stayCohort studyCommon complicationHospital dischargePericardial effusionCardiorespiratory failurePrimary outcomeProcedural characteristicsComplicationsPatientsHospitalStudy periodBackground ComplicationsPotential disparitiesFibrillation
2020
Newly diagnosed diabetes and outcomes after acute myocardial infarction in young adults
Ding Q, Spatz ES, Lipska KJ, Lin H, Spertus JA, Dreyer RP, Whittemore R, Funk M, Bueno H, Krumholz HM. Newly diagnosed diabetes and outcomes after acute myocardial infarction in young adults. Heart 2020, 107: 657-666. PMID: 33082173, PMCID: PMC8005796, DOI: 10.1136/heartjnl-2020-317101.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHealth statusDischarge diagnosisPharmacological treatmentMyocardial infarctionShort-term health statusYoung AMI Patients (VIRGO) studyDisease-specific health statusYoung adultsQuality of lifeHospital complicationsHospital mortalityMedication initiationBaseline characteristicsClinical outcomesDiabetesPatientsDiagnosisPatient studiesMonthsComplicationsInfarctionSignificant differencesOutcomesMortality
2019
Institutional Variation in Quality of Cardiovascular Implantable Electronic Device Implantation: A Cohort Study.
Ranasinghe I, Labrosciano C, Horton D, Ganesan A, Curtis JP, Krumholz HM, McGavigan A, Hossain S, Air T, Hariharaputhiran S. Institutional Variation in Quality of Cardiovascular Implantable Electronic Device Implantation: A Cohort Study. Annals Of Internal Medicine 2019, 171: 309-317. PMID: 31357210, DOI: 10.7326/m18-2810.Peer-Reviewed Original ResearchConceptsCardiovascular implantable electronic devicesComplication rateCohort studyCIED complicationsCardiovascular implantable electronic device (CIED) implantationMajor device-related complicationsDays of dischargeDevice-related complicationsProcedure-related complicationsImplantable electronic devicesPPM implantationMajor complicationsICD placementDevice implantationElective proceduresComplicationsHospitalCare qualityStudy periodPatientsAdministrative dataInstitutional variationNational averageImplantation
2018
Factors Associated With Return to Work After Acute Myocardial Infarction in China
Jiang Z, Dreyer RP, Spertus JA, Masoudi FA, Li J, Zheng X, Li X, Wu C, Bai X, Hu S, Wang Y, Krumholz HM, Chen H. Factors Associated With Return to Work After Acute Myocardial Infarction in China. JAMA Network Open 2018, 1: e184831. PMID: 30646375, PMCID: PMC6324382, DOI: 10.1001/jamanetworkopen.2018.4831.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionIndex acute myocardial infarctionHistory of smokingMyocardial infarctionHospital complicationsBaseline characteristicsFemale sexPatient baseline characteristicsProspective cohort studyLower likelihoodAcute myocardial infarction hospitalizationsLogistic regression modelsMyocardial infarction hospitalizationsCohort studyPatient factorsChina PatientProspective studyChinese patientsMAIN OUTCOMEInfarctionPatientsMonthsHospitalizationComplicationsSmoking
2016
Long-Term Risk for Device-Related Complications and Reoperations After Implantable Cardioverter-Defibrillator Implantation: An Observational Cohort Study.
Ranasinghe I, Parzynski CS, Freeman JV, Dreyer RP, Ross JS, Akar JG, Krumholz HM, Curtis JP. Long-Term Risk for Device-Related Complications and Reoperations After Implantable Cardioverter-Defibrillator Implantation: An Observational Cohort Study. Annals Of Internal Medicine 2016, 165: 20-29. PMID: 27135392, DOI: 10.7326/m15-2732.Peer-Reviewed Original ResearchICD-related complicationsNational Cardiovascular Data RegistryObservational cohort studyDevice-related complicationsICD implantationLong-term riskCohort studyMedicare feeNational Cardiovascular Data Registry ICD RegistryImplantable cardioverter defibrillator implantationImplantable cardioverter-defibrillator placementCardioverter-defibrillator implantationService claims dataCRT-D devicesSingle-chamber devicesCumulative incidenceNonfatal outcomesICD RegistryService patientsBlack raceFemale sexReoperationAmerican CollegeClaims dataComplications
2007
Failure to Rescue
Horwitz LI, Cuny JF, Cerese J, Krumholz HM. Failure to Rescue. Medical Care 2007, 45: 283-287. PMID: 17496710, DOI: 10.1097/01.mlr.0000250226.33094.d4.Peer-Reviewed Original ResearchConceptsChart reviewQuality Patient Safety IndicatorsRetrospective chart reviewPatient safety indicatorsRate of deathAdministrative dataHospital complicationsComplication typePatient agePatient characteristicsPrimary outcomeNonsurgical casesInsurance statusComplicationsHealthcare ResearchPatientsMortalityConsortium institutionsAgeSafety indicatorsFailureReviewHospitalizationAdmissionCases
2000
Perceptions of Benefit and Risk of Patients Undergoing First‐time Elective Percutaneous Coronary Revascularization
Holmboe E, Fiellin D, Cusanelli E, Remetz M, Krumholz H. Perceptions of Benefit and Risk of Patients Undergoing First‐time Elective Percutaneous Coronary Revascularization. Journal Of General Internal Medicine 2000, 15: 632-637. PMID: 11029677, PMCID: PMC1495592, DOI: 10.1046/j.1525-1497.2000.90823.x.Peer-Reviewed Original ResearchConceptsElective percutaneous coronary revascularizationPercutaneous coronary revascularizationMajority of patientsCoronary revascularizationAbnormal diagnostic test resultsFuture myocardial infarctionRelief of symptomsRisk of patientsDiagnostic test resultsConsecutive patientsMean ageMyocardial infarctionLong-term benefitsPossible complicationsPotential complicationsPatient decisionPatient expectationsPatientsSemistructured questionnaireRevascularizationComplicationsRiskPerceptions of benefitsPotential riskQuestionnaire