2001
The association between white blood cell count and acute myocardial infarction mortality in patients ≥65 years of age: findings from the cooperative cardiovascular project
Barron H, Harr S, Radford M, Wang Y, Krumholz H. The association between white blood cell count and acute myocardial infarction mortality in patients ≥65 years of age: findings from the cooperative cardiovascular project. Journal Of The American College Of Cardiology 2001, 38: 1654-1661. PMID: 11704377, DOI: 10.1016/s0735-1097(01)01613-8.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionWhite blood cell countBlood cell countWBC countWhite blood cellsYears of ageIndependent predictorsCell countDevelopment of AMIAcute myocardial infarction mortalityHospital clinical eventsLong-term mortalityRisk-stratify patientsCoronary artery diseaseCooperative Cardiovascular Project databaseStrong independent predictorCooperative Cardiovascular ProjectMyocardial infarction mortalityImportant clinical implicationsHospital mortalityArtery diseaseHospital eventsClinical eventsHighest quintileLowest quintile
1999
Comparing AMI Mortality Among Hospitals in Patients 65 Years of Age and Older
Krumholz H, Chen J, Wang Y, Radford M, Chen Y, Marciniak T. Comparing AMI Mortality Among Hospitals in Patients 65 Years of Age and Older. Circulation 1999, 99: 2986-2992. PMID: 10368115, DOI: 10.1161/01.cir.99.23.2986.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionWhite blood cell countPatients 65 yearsSystolic blood pressureCongestive heart failureMedical chart reviewReceiver-operating characteristic curveBlood cell countRisk-adjusted outcomesYears of ageAdministrative billing codesRisk-adjustment modelsHospital outcomesSerum creatinineChart reviewDerivation cohortHeart failurePatient characteristicsBlood pressureCardiac arrestValidation cohortCandidate predictor variablesAMI mortalityBilling codes
1989
Community-acquired bacteremia in patients with acquired immunodeficiency syndrome: clinical presentation, bacteriology, and outcome
Krumholz H, Sande M, Lo B. Community-acquired bacteremia in patients with acquired immunodeficiency syndrome: clinical presentation, bacteriology, and outcome. The American Journal Of Medicine 1989, 86: 776-779. PMID: 2729338, DOI: 10.1016/0002-9343(89)90472-5.Peer-Reviewed Original ResearchConceptsCommunity-acquired bacteremiaWhite blood cell countAbnormal vital signsBlood cell countVital signsClinical presentationImmunodeficiency syndromeAIDS patientsCell countBacterial infectionsIndwelling central venous lineSan Francisco General HospitalPossibility of bacteremiaSource of bacteremiaHours of admissionNormal vital signsCentral venous lineIntravenous drug usersAdmission of patientsPositive blood culturesBroad-spectrum antibioticsEmpiric therapyHospital outcomesPatient chartsTreatable infection