2020
Renin–angiotensin system blockers and susceptibility to COVID-19: an international, open science, cohort analysis
Morales DR, Conover MM, You SC, Pratt N, Kostka K, Duarte-Salles T, Fernández-Bertolín S, Aragón M, DuVall SL, Lynch K, Falconer T, van Bochove K, Sung C, Matheny ME, Lambert CG, Nyberg F, Alshammari TM, Williams AE, Park RW, Weaver J, Sena AG, Schuemie MJ, Rijnbeek PR, Williams RD, Lane JCE, Prats-Uribe A, Zhang L, Areia C, Krumholz HM, Prieto-Alhambra D, Ryan PB, Hripcsak G, Suchard MA. Renin–angiotensin system blockers and susceptibility to COVID-19: an international, open science, cohort analysis. The Lancet Digital Health 2020, 3: e98-e114. PMID: 33342753, PMCID: PMC7834915, DOI: 10.1016/s2589-7500(20)30289-2.Peer-Reviewed Original ResearchAngiotensin receptor blockersCalcium channel blockersAcute respiratory distress syndromeAcute kidney injuryHospital admissionRespiratory distress syndromeCOVID-19 diagnosisKidney injuryDistress syndromeDrug classesCohort analysisCOVID-19Renin-angiotensin system blockersThiazide-like diureticsBaseline patient characteristicsUse of ACEIsPost-authorisation studiesUK National InstituteRelative risk differenceNational InstituteCombination useMedical Research CouncilAustralian National HealthElectronic health recordsAntihypertensive users
2006
Health Status Identifies Heart Failure Outpatients at Risk for Hospitalization or Death
Heidenreich PA, Spertus JA, Jones PG, Weintraub WS, Rumsfeld JS, Rathore SS, Peterson ED, Masoudi FA, Krumholz HM, Havranek EP, Conard MW, Williams RE, Consortium C. Health Status Identifies Heart Failure Outpatients at Risk for Hospitalization or Death. Journal Of The American College Of Cardiology 2006, 47: 752-756. PMID: 16487840, DOI: 10.1016/j.jacc.2005.11.021.Peer-Reviewed Original ResearchConceptsKansas City Cardiomyopathy QuestionnaireB-type natriuretic peptideKCCQ summary scoreHeart failureKCCQ scoresHealth status measuresClinical conditionsNew York Heart Association functional class IVSummary scoresStatus measuresFunctional class IVIschemic HF etiologyLower KCCQ scoresSequential multivariable modelsBaseline patient characteristicsHeart failure outpatientsPatient's clinical conditionProportional hazards regressionBNP levelsHF etiologyHF hospitalizationHF admissionsHF patientsPatient characteristicsWalk distance
1998
Admission to Hospitals With On-Site Cardiac Catheterization Facilities
Krumholz H, Chen J, Murillo J, Cohen D, Radford M. Admission to Hospitals With On-Site Cardiac Catheterization Facilities. Circulation 1998, 98: 2010-2016. PMID: 9808598, DOI: 10.1161/01.cir.98.19.2010.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAngioplasty, Balloon, CoronaryCardiac Care FacilitiesCardiac CatheterizationCohort StudiesCoronary Artery BypassFemaleHealth Care CostsHospital MortalityHospitalizationHumansLength of StayMaleMedical RecordsPilot ProjectsRetrospective StudiesTime FactorsTreatment OutcomeConceptsSite cardiac catheterization facilitiesCardiac catheterization facilitiesAcute myocardial infarctionCatheterization facilitiesType of hospitalReadmission ratesCardiac proceduresMyocardial infarctionHospital costsMortality rateGood short-term clinical outcomesShort-term clinical outcomesLong-term mortality ratesAdjusted readmission ratesCardiac catheterization ratesBaseline patient characteristicsLong-term mortalityRetrospective cohort studyLower readmission ratesElderly Medicare patientsSignificant differencesCatheterization ratesRevascularization ratesCardiac catheterizationCohort study