2016
Association of Guideline-Based Admission Treatments and Life Expectancy After Myocardial Infarction in Elderly Medicare Beneficiaries
Bucholz EM, Butala NM, Normand SL, Wang Y, Krumholz HM. Association of Guideline-Based Admission Treatments and Life Expectancy After Myocardial Infarction in Elderly Medicare Beneficiaries. Journal Of The American College Of Cardiology 2016, 67: 2378-2391. PMID: 27199062, PMCID: PMC5097252, DOI: 10.1016/j.jacc.2016.03.507.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAgedAspirinFemaleFollow-Up StudiesGuideline AdherenceHospitalizationHumansLife ExpectancyMaleMedicareMyocardial InfarctionPercutaneous Coronary InterventionPlatelet Aggregation InhibitorsPractice Guidelines as TopicThrombolytic TherapyTime-to-TreatmentUnited StatesConceptsAcute myocardial infarctionPrimary percutaneous coronary interventionGuideline-based therapyYears of lifeAdmission therapyLife expectancyMyocardial infarctionMedicare beneficiariesCox proportional hazards regressionAcute reperfusion therapyLate survival benefitReceipt of aspirinPercutaneous coronary interventionLong-term outcomesProportional hazards regressionCooperative Cardiovascular ProjectElderly Medicare beneficiariesDose-response relationshipAssociation of GuidelineShort life expectancyLonger life expectancyReperfusion therapyCoronary interventionD2B timeElderly patients
2007
Acute Reperfusion Therapy in ST-Elevation Myocardial Infarction from 1994-2003
Nallamothu BK, Blaney ME, Morris SM, Parsons L, Miller DP, Canto JG, Barron HV, Krumholz HM, Investigators R. Acute Reperfusion Therapy in ST-Elevation Myocardial Infarction from 1994-2003. The American Journal Of Medicine 2007, 120: 693.e1-693.e8. PMID: 17679128, PMCID: PMC2020513, DOI: 10.1016/j.amjmed.2007.01.028.Peer-Reviewed Original ResearchConceptsAcute reperfusion therapyST-elevation myocardial infarctionReperfusion therapyMyocardial infarctionIdeal patientPrimary percutaneous coronary interventionPercutaneous coronary interventionNational performance measuresChest painCoronary interventionFibrinolytic therapySymptom onsetNational registryPatientsTherapyInfarctionKey subgroupsAppropriate utilizationTime periodRecent time periodPainRegistryCohortContemporary useImportant opportunity
2004
Racial and Ethnic Differences in Time to Acute Reperfusion Therapy for Patients Hospitalized With Myocardial Infarction
Bradley EH, Herrin J, Wang Y, McNamara RL, Webster TR, Magid DJ, Blaney M, Peterson ED, Canto JG, Pollack CV, Krumholz HM. Racial and Ethnic Differences in Time to Acute Reperfusion Therapy for Patients Hospitalized With Myocardial Infarction. JAMA 2004, 292: 1563-1572. PMID: 15467058, DOI: 10.1001/jama.292.13.1563.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAngioplasty, Balloon, CoronaryAsian PeopleBlack PeopleFemaleHispanic or LatinoHospitalsHumansInsurance, HospitalizationMaleMiddle AgedMyocardial InfarctionOutcome Assessment, Health CarePatient AdmissionRetrospective StudiesSocioeconomic FactorsThrombolytic TherapyTime and Motion StudiesTime FactorsUnited StatesWhite PeopleConceptsST-segment elevation myocardial infarctionAcute reperfusion therapyElevation myocardial infarctionMyocardial infarctionReperfusion therapyAfrican American/BlackBalloon timeInsurance statusAmerican/BlackEthnic differencesPercutaneous coronary interventionBundle branch blockAsian/Pacific IslandersHealth care disparitiesRace/ethnicity differencesRace/ethnicityClinical characteristicsCoronary interventionFibrinolytic therapyHospital arrivalNonwhite patientsPrimary reperfusionWhite patientsUS cohortHospital characteristics
2003
National and State Trends in Quality of Care for Acute Myocardial Infarction Between 1994-1995 and 1998-1999: The Medicare Health Care Quality Improvement Program
Burwen DR, Galusha DH, Lewis JM, Bedinger MR, Radford MJ, Krumholz HM, Foody JM. National and State Trends in Quality of Care for Acute Myocardial Infarction Between 1994-1995 and 1998-1999: The Medicare Health Care Quality Improvement Program. JAMA Internal Medicine 2003, 163: 1430-1439. PMID: 12824092, DOI: 10.1001/archinte.163.12.1430.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAgedAged, 80 and overAngioplasty, Balloon, CoronaryAngiotensin-Converting Enzyme InhibitorsAspirinFemaleHealth Care SurveysHumansMaleMedicareMiddle AgedMyocardial InfarctionPlatelet Aggregation InhibitorsQuality Indicators, Health CareQuality of Health CareSmoking CessationThrombolytic TherapyTime FactorsUnited StatesConceptsAcute myocardial infarctionQuality of careHospital arrivalEarly administrationMedian timeMyocardial infarctionPrimary percutaneous transluminal coronary angioplastyHealth Care Quality Improvement ProgramPercutaneous transluminal coronary angioplastyAcute reperfusion therapyBeta-blocker prescriptionEnzyme inhibitor prescriptionTransluminal coronary angioplastyGuideline-recommended processesQuality Improvement ProgramPopulation-based improvementsCessation counselingReperfusion therapySystolic dysfunctionInhibitor prescriptionCoronary angioplastyThrombolytic therapyMedicare patientsTherapyTime pointsEffects of age on the quality of care provided to older patients with acute myocardial infarction
Rathore SS, Mehta RH, Wang Y, Radford MJ, Krumholz HM. Effects of age on the quality of care provided to older patients with acute myocardial infarction. The American Journal Of Medicine 2003, 114: 307-315. PMID: 12681459, DOI: 10.1016/s0002-9343(02)01531-0.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAge FactorsAgedAged, 80 and overAttitude of Health PersonnelCohort StudiesCombined Modality TherapyCoronary Care UnitsCritical CareDrug UtilizationFemaleGuideline AdherenceHealth Services AccessibilityHealth Services for the AgedHumansLogistic ModelsMaleMedicareMyocardial InfarctionOdds RatioPractice Patterns, Physicians'Quality of Health CareRisk AssessmentSurvival AnalysisThrombolytic TherapyUnited StatesConceptsAcute reperfusion therapyAcute myocardial infarctionMyocardial infarctionReperfusion therapyEffect of ageElderly patientsOlder patientsAge-associated variationsGuideline-recommended medical therapyAngiotensin-converting enzyme inhibitorGuideline-indicated therapiesPrescription of aspirinUse of aspirinCooperative Cardiovascular ProjectUse of therapiesQuality of careAcute reperfusionTreatment contraindicationsMedical therapyComorbid conditionsACE inhibitorsMedicare patientsHospital effectsPatientsEnzyme inhibitorsValidity of a Simple ST-Elevation Acute Myocardial Infarction Risk Index
Rathore SS, Weinfurt KP, Gross CP, Krumholz HM. Validity of a Simple ST-Elevation Acute Myocardial Infarction Risk Index. Circulation 2003, 107: 811-816. PMID: 12591749, DOI: 10.1161/01.cir.0000049743.45748.02.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCalibrationCohort StudiesElectrocardiographyFemaleHumansInpatientsMaleMyocardial InfarctionMyocardial ReperfusionPredictive Value of TestsPrognosisRandomized Controlled Trials as TopicReproducibility of ResultsRetrospective StudiesRiskRisk AssessmentSurvival AnalysisConceptsSimple risk indexCommunity-based cohortRCT populationMyocardial infarctionST-segment elevation myocardial infarctionST-elevation myocardial infarctionMyocardial Infarction (TIMI) risk indexRandomized clinical trial dataAcute reperfusion therapyPatients 65 yearsRisk stratification scoresElevation myocardial infarctionCommunity-based populationDistribution of patientsHigh-risk groupLow-risk groupRisk stratification indexClinical trial dataYears of ageRisk indexReperfusion therapyRisk score distributionPrognostic scoreMortality estimatesGeneral population
2002
Evaluation of a Consumer-Oriented Internet Health Care Report Card: The Risk of Quality Ratings Based on Mortality Data
Krumholz HM, Rathore SS, Chen J, Wang Y, Radford MJ. Evaluation of a Consumer-Oriented Internet Health Care Report Card: The Risk of Quality Ratings Based on Mortality Data. JAMA 2002, 287: 1277-1287. PMID: 11886319, DOI: 10.1001/jama.287.10.1277.Peer-Reviewed Original ResearchConceptsProcess of careMortality rateHospital ratingEnzyme inhibitorsUS acute care hospitalsSystematic medical record reviewIndividual hospitalsStudy periodAcute myocardial infarction mortalityAcute reperfusion therapyReperfusion therapy ratesMedical record reviewService beneficiaries 65 yearsCooperative Cardiovascular ProjectBeneficiaries 65 yearsAcute care hospitalsMyocardial infarction mortalityHealth care report cardsQuality of careCare report cardsHospital performanceReperfusion therapyTherapy ratesCare hospitalRecord review