Regulator of G‐protein signaling 6 (RGS6) expression in human substantia nigra pars compacta (SNc) and loss in Parkinson's disease (PD)
Luo Z, Ahlers K, Yang J, Chakravarti B, Stevens H, Narayanan N, Fisher R. Regulator of G‐protein signaling 6 (RGS6) expression in human substantia nigra pars compacta (SNc) and loss in Parkinson's disease (PD). The FASEB Journal 2017, 31 DOI: 10.1096/fasebj.31.1_supplement.659.23.Peer-Reviewed Original ResearchSubstantia nigra pars compactaSNc DA neuronsDA neuronsParkinson's diseasePD patientsHuman substantia nigra pars compactaPotential novel therapeutic targetCritical neuroprotective roleDA neuron degenerationTyrosine hydroxylase expressionNovel therapeutic targetDevastating neurodegenerative disorderAge-dependent lossSNc neuronsMotor deficitsNeuroprotective rolePars compactaPathogenic linkNeuron degenerationPD treatmentDopamine neuronsHydroxylase expressionBehavioral deficitsDA contentImmunohistochemical analysis