2021
Left ventricular myocardial strain and tissue characterization by cardiac magnetic resonance imaging in immune checkpoint inhibitor associated cardiotoxicity
Higgins AY, Arbune A, Soufer A, Ragheb E, Kwan JM, Lamy J, Henry M, Cuomo JR, Charifa A, Gallegos C, Hull S, Coviello JS, Bader AS, Peters DC, Huber S, Mojibian HR, Sinusas AJ, Kluger H, Baldassarre LA. Left ventricular myocardial strain and tissue characterization by cardiac magnetic resonance imaging in immune checkpoint inhibitor associated cardiotoxicity. PLOS ONE 2021, 16: e0246764. PMID: 33606757, PMCID: PMC7895343, DOI: 10.1371/journal.pone.0246764.Peer-Reviewed Original ResearchConceptsGlobal longitudinal strainImmune checkpoint inhibitorsLate gadolinium enhancementRecovery of LVEFLake Louise criteriaCheckpoint inhibitorsNormal LVEFAverage global longitudinal strainPresence of LGEAbnormal global longitudinal strainCardiac magnetic resonance imagingCorrect clinical contextEvaluation of myocarditisLeft ventricular dysfunctionVentricular ejection fractionDiagnosis of myocarditisLeft ventricular strainCardiac magnetic resonanceLeft ventricular myocardial strainOvert left ventricular dysfunctionVentricular myocardial strainMagnetic resonance imagingAtrial strainVentricular dysfunctionVentricular strain
2016
Systemic Inflammatory Disease and its Association With Type II Endoleak and Late Interventions After Endovascular Aneurysm Repair
Shalaby SY, Foster TR, Hall MR, Brownson KE, Vasilas P, Federman DG, Mojibian HR, Dardik A. Systemic Inflammatory Disease and its Association With Type II Endoleak and Late Interventions After Endovascular Aneurysm Repair. JAMA Surgery 2016, 151: 147. PMID: 26501863, DOI: 10.1001/jamasurg.2015.3219.Peer-Reviewed Original ResearchConceptsSystemic inflammatory diseaseEndovascular aneurysm repairType II endoleakAneurysm repairInflammatory diseasesPostoperative complicationsSignificant endoleakChronic inflammationSac expansionVeterans Affairs Connecticut Healthcare SystemLate sac expansionPersistent autoimmune responseSac diameter increaseSimilar comorbid conditionsMajor postoperative complicationsOverall postoperative complicationsAbdominal aortic aneurysmMore endoleaksYearly imagingAortic remodelingRetrospective reviewComorbid conditionsAutoimmune responseSac ruptureAortic aneurysm