Molecular Reconstruction of Nodes of Ranvier after Remyelination by Transplanted Olfactory Ensheathing Cells in the Demyelinated Spinal Cord
Sasaki M, Black JA, Lankford KL, Tokuno HA, Waxman SG, Kocsis JD. Molecular Reconstruction of Nodes of Ranvier after Remyelination by Transplanted Olfactory Ensheathing Cells in the Demyelinated Spinal Cord. Journal Of Neuroscience 2006, 26: 1803-1812. PMID: 16467529, PMCID: PMC2605396, DOI: 10.1523/jneurosci.3611-05.2006.Peer-Reviewed Original ResearchConceptsDemyelinated spinal cordSpecific membrane domainsSpinal cordVoltage-gated ion channelsGreen fluorescent proteinTransplanted Olfactory Ensheathing CellsMature NodalMembrane domainsSpinal cord demyelinationOlfactory Ensheathing CellsVivo electrophysiological recordingsFluorescent proteinJuxtaparanodal domainsMolecular reconstructionIon channelsMature nodesRemyelinated axonsExtensive remyelinationUninjured axonsKv channelsDemyelinated axonsDonor ratsCentral axonsGlial cellsJuxtaparanodal region