2013
Functional Analyses of TNFR2 in Physiological and Pathological Retina AngiogenesisTNFR2 Mediates Retinal Angiogenesis
Wan T, Xu Z, Zhou HJ, Zhang H, Luo Y, Li Y, Min W. Functional Analyses of TNFR2 in Physiological and Pathological Retina AngiogenesisTNFR2 Mediates Retinal Angiogenesis. Investigative Ophthalmology & Visual Science 2013, 54: 211-221. PMID: 23188724, PMCID: PMC3544528, DOI: 10.1167/iovs.12-10364.Peer-Reviewed Original ResearchMeSH KeywordsAngiopoietin-2AnimalsAnimals, NewbornCell SurvivalDisease Models, AnimalEndothelium, VascularEpithelial CellsGene ExpressionHumansHypoxiaInfant, NewbornMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicNeovascularization, PathologicNF-kappa BOxygenProtein-Tyrosine KinasesReceptor, TIE-2Receptors, Tumor Necrosis Factor, Type IIRetinaRetinal NeovascularizationRetinopathy of PrematurityVascular Endothelial Growth Factor Receptor-2ConceptsTumor necrosis factor receptor 2Wild-type C57BL/6 miceTNFR2 deletionTNFR2-KOOIR modelOxygen-induced retinopathy modelNecrosis factor receptor 2Pathological neovascular tuftsRetinal vascular repairVascular ECsRetinal vascular developmentIschemia-induced revascularizationRetinal vasculature developmentFactor receptor 2Vascular endothelial cellsPreretinal neovascularizationVascular developmentC57BL/6 miceNeovascular tuftsKO miceNeonatal miceIsolectin stainingVascular repairBone marrow kinasePostnatal day
2010
Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis
Xie D, Gore C, Liu J, Pong RC, Mason R, Hao G, Long M, Kabbani W, Yu L, Zhang H, Chen H, Sun X, Boothman DA, Min W, Hsieh JT. Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 2485-2490. PMID: 20080667, PMCID: PMC2823864, DOI: 10.1073/pnas.0908133107.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBeta CateninBlotting, WesternCadherinsCell LineCell Line, TumorCell MovementEpithelial CellsGene ExpressionHumansImmunohistochemistryMaleMesodermMiceMice, NudeNeoplasm MetastasisNeoplasms, ExperimentalProstatic NeoplasmsRas GTPase-Activating ProteinsReverse Transcriptase Polymerase Chain ReactionRNA, Small InterferingTCF Transcription FactorsTransfectionTransplantation, HeterologousVimentinConceptsProstate cancerMesenchymal transitionDAB2IP expressionCarcinoma cellsMultiple lymph nodesMetastatic prostate cancerDistant organ metastasisAggressive prostate cancerMetastatic PCa cellsProstate cancer metastasisClinical prostate cancer specimensHuman normal prostatePotential therapeutic targetXenograft mouse modelProstate cancer specimensProstate carcinoma cellsLymph nodesOrgan metastasisPCa cellsRole of DAB2IPPrognostic biomarkerPCa metastasisKnockout miceTherapeutic targetHuman carcinoma cells