Identification of Piwil2-Like (PL2L) Proteins that Promote Tumorigenesis
Ye Y, Yin DT, Chen L, Zhou Q, Shen R, He G, Yan Q, Tong Z, Issekutz AC, Shapiro CL, Barsky SH, Lin H, Li JJ, Gao JX. Identification of Piwil2-Like (PL2L) Proteins that Promote Tumorigenesis. PLOS ONE 2010, 5: e13406. PMID: 20975993, PMCID: PMC2958115, DOI: 10.1371/journal.pone.0013406.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArgonaute ProteinsBase SequenceCell Line, TumorCell Transformation, NeoplasticDNA PrimersFemaleHumansImmunohistochemistryMaleMiceMice, Inbred C57BLNeoplasm MetastasisNeoplasmsNF-kappa BPrecancerous ConditionsProteinsProto-Oncogene Proteins c-bcl-2Reverse Transcriptase Polymerase Chain ReactionRNA InterferenceRNA, MessengerSTAT3 Transcription FactorStem CellsTransplantation, HeterologousUp-RegulationConceptsGermline stem cellsStem cellsAGO gene familyCell cycle entryPrecancerous stem cellsTumor developmentTumor cell survivalBCL2 gene expressionGene familyCycle entryGene expressionTumor cellsNF-κBCell survivalAnticancer drug developmentPIWIL2S phaseGene exonsNovel insightsProteinMouse tumor cellsCancer developmentNovel monoclonal antibodyTranscriptsTypes of human