MILI, a PIWI-interacting RNA-binding Protein, Is Required for Germ Line Stem Cell Self-renewal and Appears to Positively Regulate Translation*
Unhavaithaya Y, Hao Y, Beyret E, Yin H, Kuramochi-Miyagawa S, Nakano T, Lin H. MILI, a PIWI-interacting RNA-binding Protein, Is Required for Germ Line Stem Cell Self-renewal and Appears to Positively Regulate Translation*. Journal Of Biological Chemistry 2008, 284: 6507-6519. PMID: 19114715, PMCID: PMC2649106, DOI: 10.1074/jbc.m809104200.Peer-Reviewed Original ResearchConceptsGerm line stem cellsStem cellsArgonaute/PIWI protein familyMicro-RNA pathwayGerm line developmentMammalian stem cellsPIWI-interacting RNAsCap-binding complexRNA-binding proteinPIWI protein familyCellular mRNA levelsStem cell populationSelf-renewing divisionsArgonaute functionsPIWI proteinsRegulates TranslationPIWI subfamiliesEpigenetic regulationProtein familyCell maintenanceRNA interferenceChromatoid bodyMILIMolecular mechanismsEarly spermatocytes