The stem-cell niche theory: lessons from flies
Lin H. The stem-cell niche theory: lessons from flies. Nature Reviews Genetics 2002, 3: 931-940. PMID: 12459723, DOI: 10.1038/nrg952.Peer-Reviewed Original ResearchConceptsStem cell nicheSomatic stem cellsStem cellsTesticular stem cell nicheGermline stem cellsTerminal filament cellsSelf-renewing divisionsOogenic functionEpidermal growth factor receptorUnpaired ligandAdherens junctionsMammalian systemsTesticular nicheOvarian nicheGrowth factor receptorHub cellsPathway functionNiche theoryFilament cellsGermlineCell adhesionNicheFactor receptorPathwayFlies