Piecing Together the Mosaic of Early Mammalian Development through MicroRNAs*
Blakaj A, Lin H. Piecing Together the Mosaic of Early Mammalian Development through MicroRNAs*. Journal Of Biological Chemistry 2008, 283: 9505-9508. PMID: 18272516, PMCID: PMC2442291, DOI: 10.1074/jbc.r800002200.Peer-Reviewed Original ResearchConceptsRole of miRNAsES cellsEarly mammalian developmentMammalian ES cellsDozens of miRNAsRNase III enzymeCluster of miRNAsES cell differentiationEmbryonic stem cellsRNA biogenesisMammalian embryogenesisMammalian developmentLineage specificationMicroRNA pathwayMiR-290MiRNA biogenesisEmbryonic developmentNuclear proteinsCell differentiationMiRNAsStem cellsBiogenesisEarly developmentCellsCrucial role