2021
Spatial Characteristics of Colonic Mucosa-Associated Gut Microbiota in Humans
Jiao L, Kourkoumpetis T, Hutchinson D, Ajami N, Hoffman K, White D, Graham D, Hair C, Shah R, Kanwal F, Jarbrink-Sehgal M, Husain N, Hernaez R, Hou J, Cole R, Velez M, Ketwaroo G, Kramer J, El-Serag H, Petrosino J. Spatial Characteristics of Colonic Mucosa-Associated Gut Microbiota in Humans. Microbial Ecology 2021, 83: 811-821. PMID: 34223947, DOI: 10.1007/s00248-021-01789-6.Peer-Reviewed Original ResearchConceptsAmplicon sequence variantsBacterial community compositionCommunity compositionMucosa-associated gut microbiotaTaxonomic structureSignificant differencesRelative abundanceColonic biopsiesEscherichia/ShigellaInter-individual variabilityColonic segmentsColon segmentsFunctional capacityGut microbiotaLarge intestineFree adultsColonic bacteriaRRNA geneCompositional dissimilarityMajor phylaFecal bacteriaSequencing dataLimited data
2020
Accuracy of a novel noninvasive secretin-enhanced MRCP severity index scoring system for diagnosis of chronic pancreatitis: correlation with EUS-based Rosemont criteria
Souza D, Alessandrino F, Ketwaroo G, Sawhney M, Mortele K. Accuracy of a novel noninvasive secretin-enhanced MRCP severity index scoring system for diagnosis of chronic pancreatitis: correlation with EUS-based Rosemont criteria. La Radiologia Medica 2020, 125: 816-826. PMID: 32266691, DOI: 10.1007/s11547-020-01181-3.Peer-Reviewed Original Research
2017
The Impact of Risk Factors of Chronic Pancreatitis on Secretin Pancreatic Function Testing
Kothari D, Ketwaroo G, Freedman S, Sheth S. The Impact of Risk Factors of Chronic Pancreatitis on Secretin Pancreatic Function Testing. Pancreas 2017, 46: 887-890. PMID: 28697128, DOI: 10.1097/mpa.0000000000000871.Peer-Reviewed Original ResearchConceptsRecurrent acute pancreatitisPeak bicarbonate concentrationHistory of APAcute pancreatitisRisk factorsPancreatic function testingChronic pancreatitisLocal complicationsFunction testingFemale sexBicarbonate concentrationRetrospective reviewUnivariate analysisFamily historyTobacco usePancreatitisPatientsMultivariate analysisAlcohol useComplicationsSignificant differencesSexFactorsHistoryComparison of Combined Endoscopic Ultrasonography and Endoscopic Secretin Testing With the Traditional Secretin Pancreatic Function Test in Patients With Suspected Chronic Pancreatitis
Kothari D, Ketwaroo G, Sawhney M, Freedman S, Sheth S. Comparison of Combined Endoscopic Ultrasonography and Endoscopic Secretin Testing With the Traditional Secretin Pancreatic Function Test in Patients With Suspected Chronic Pancreatitis. Pancreas 2017, 46: 770-775. PMID: 28609365, DOI: 10.1097/mpa.0000000000000829.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomarkersCross-Over StudiesEndoscopes, GastrointestinalEndoscopy, GastrointestinalEndosonographyFeasibility StudiesFemaleHumansMaleMiddle AgedPancreatic Function TestsPancreatic JuicePancreatitis, ChronicPredictive Value of TestsPrognosisProspective StudiesReproducibility of ResultsSecretinTime FactorsWorkflowConceptsChronic pancreatitisPeak bicarbonate concentrationPancreatic function testsEndoscopic ultrasonographyFunction testsPoor concordanceProspective crossover studyPancreatic function testingFunctional testsBicarbonate concentrationPeak bicarbonateSecretin testingCrossover studyFunction testingTest concordanceDiscordant findingsFunctional assessmentPatientsImproved concordancePancreatitisSignificant correlationUltrasonographyConcordanceFeasible testCutoff
2016
Risk Profiles for Barrett’s Esophagus Differ between New and Prevalent, and Long- and Short-Segment Cases
Tan M, Murrey-Ittmann J, Nguyen T, Ketwaroo G, El-Serag H, Thrift A. Risk Profiles for Barrett’s Esophagus Differ between New and Prevalent, and Long- and Short-Segment Cases. PLOS ONE 2016, 11: e0169250. PMID: 28036381, PMCID: PMC5201279, DOI: 10.1371/journal.pone.0169250.Peer-Reviewed Original ResearchConceptsSpecialized intestinal metaplasiaShort-segment BELong-segment BEPrimary care controlsH. pylori infectionRisk factorsGERD symptomsElective esophagogastroduodenoscopyEndoscopy controlsCare controlPylori infectionCase definitionBE casesControl groupGastroesophageal reflux disease symptomsMultivariate logistic regression modelFrequent GERD symptomsPrimary care clinicsCross-sectional studyVeterans Affairs centersLogistic regression modelsEligible patientsH2RA useMedication useCare clinics
2013
Defining the Accuracy of Secretin Pancreatic Function Testing in Patients With Suspected Early Chronic Pancreatitis
Ketwaroo G, Brown A, Young B, Kheraj R, Sawhney M, Mortele K, Najarian R, Tewani S, Dasilva D, Freedman S, Sheth S. Defining the Accuracy of Secretin Pancreatic Function Testing in Patients With Suspected Early Chronic Pancreatitis. The American Journal Of Gastroenterology 2013, 108: 1360. PMID: 23711627, PMCID: PMC5388854, DOI: 10.1038/ajg.2013.148.Peer-Reviewed Original ResearchConceptsEarly chronic pancreatitisNegative predictive valueChronic pancreatitisPancreatic function testingPositive predictive valueHistologic evidenceFunction testingPredictive valuePancreatic imagingTertiary care institutionMedian followPositive patientsRetrospective reviewPancreatic functionMedical recordsPancreatitisPatientsDiagnostic accuracyCharacteristic symptomsCare institutionsFollowSubsequent developmentImagingEvidenceSymptoms
2007
Reduced microstructural integrity of the white matter underlying anterior cingulate cortex is associated with increased saccadic latency in schizophrenia
Manoach D, Ketwaroo G, Polli F, Thakkar K, Barton J, Goff D, Fischl B, Vangel M, Tuch D. Reduced microstructural integrity of the white matter underlying anterior cingulate cortex is associated with increased saccadic latency in schizophrenia. NeuroImage 2007, 37: 599-610. PMID: 17590354, DOI: 10.1016/j.neuroimage.2007.04.062.Peer-Reviewed Original ResearchConceptsAnterior cingulate cortexDiffusion tensor imagingWhite matterVolitional saccadesCingulate cortexFractional anisotropySaccadic latencyMicrostructural integrityLonger saccadic latenciesRight hemisphereCingulate white matterWhite matter abnormalitiesAnterior cingulum bundleOcular motor controlFrontal eye fieldMedicated schizophrenia outpatientsSaccadic eye movementsPosterior parietal cortexInter-individual variabilityMedicated schizophreniaHealthy controlsProlonged latencyCortical componentsSurface-based coordinate systemEye field