2021
Spatial Characteristics of Colonic Mucosa-Associated Gut Microbiota in Humans
Jiao L, Kourkoumpetis T, Hutchinson D, Ajami N, Hoffman K, White D, Graham D, Hair C, Shah R, Kanwal F, Jarbrink-Sehgal M, Husain N, Hernaez R, Hou J, Cole R, Velez M, Ketwaroo G, Kramer J, El-Serag H, Petrosino J. Spatial Characteristics of Colonic Mucosa-Associated Gut Microbiota in Humans. Microbial Ecology 2021, 83: 811-821. PMID: 34223947, DOI: 10.1007/s00248-021-01789-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultColonFecesGastrointestinal MicrobiomeHumansIntestinal MucosaRNA, Ribosomal, 16SVerrucomicrobiaConceptsAmplicon sequence variantsBacterial community compositionCommunity compositionMucosa-associated gut microbiotaTaxonomic structureSignificant differencesRelative abundanceColonic biopsiesEscherichia/ShigellaInter-individual variabilityColonic segmentsColon segmentsFunctional capacityGut microbiotaLarge intestineFree adultsColonic bacteriaRRNA geneCompositional dissimilarityMajor phylaFecal bacteriaSequencing dataLimited data
2019
Dietary quality and the colonic mucosa–associated gut microbiome in humans
Liu Y, Ajami N, El-Serag H, Hair C, Graham D, White D, Chen L, Wang Z, Plew S, Kramer J, Cole R, Hernaez R, Hou J, Husain N, Jarbrink-Sehgal M, Kanwal F, Ketwaroo G, Natarajan Y, Shah R, Velez M, Mallepally N, Petrosino J, Jiao L. Dietary quality and the colonic mucosa–associated gut microbiome in humans. American Journal Of Clinical Nutrition 2019, 110: 701-712. PMID: 31291462, PMCID: PMC6736447, DOI: 10.1093/ajcn/nqz139.Peer-Reviewed Original ResearchConceptsTotal HEIColonic mucosaHigher BacteroidesDietary qualityGut microbiomeCross-sectional observational studyLower scoresColonic mucosal biopsiesHealthy Eating IndexDifferent colon segmentsMucosal biopsiesMultivariable analysisObservational studyColon segmentsDietary consumptionHealthy individualsMultivariate analysisFree participantsMucosaNormal individualsFusobacteriumWhole grainsTaxonomic relative abundancesScoresSoy beverage