2019
Dietary Nutrients Involved in One-Carbon Metabolism and Colonic Mucosa-Associated Gut Microbiome in Individuals with an Endoscopically Normal Colon
Gurwara S, Ajami N, Jang A, Hessel F, Chen L, Plew S, Wang Z, Graham D, Hair C, White D, Kramer J, Kourkoumpetis T, Hoffman K, Cole R, Hou J, Husain N, Jarbrink-Sehgal M, Hernaez R, Kanwal F, Ketwaroo G, Shah R, Velez M, Natarajan Y, El-Serag H, Petrosino J, Jiao L. Dietary Nutrients Involved in One-Carbon Metabolism and Colonic Mucosa-Associated Gut Microbiome in Individuals with an Endoscopically Normal Colon. Nutrients 2019, 11: 613. PMID: 30871224, PMCID: PMC6470629, DOI: 10.3390/nu11030613.Peer-Reviewed Original ResearchMeSH KeywordsAgedBacteriaColonCross-Sectional StudiesDietFood AnalysisGastrointestinal MicrobiomeHumansIntestinal MucosaMaleMiddle AgedProspective StudiesConceptsB vitaminsDietary consumptionGut microbiotaMucosa-associated gut microbiotaConsumption of folateFood frequency questionnaireHigh consumptionFrequency questionnaireColonic biopsiesNormal colonGut microbiomeColonic bacteriaOne-carbon metabolismDaily consumptionOperational taxonomic unit classificationStatistical significanceDietary nutrientsTaxonomic relative abundancesVitaminFolateMicrobiota
2017
Comparison of Combined Endoscopic Ultrasonography and Endoscopic Secretin Testing With the Traditional Secretin Pancreatic Function Test in Patients With Suspected Chronic Pancreatitis
Kothari D, Ketwaroo G, Sawhney M, Freedman S, Sheth S. Comparison of Combined Endoscopic Ultrasonography and Endoscopic Secretin Testing With the Traditional Secretin Pancreatic Function Test in Patients With Suspected Chronic Pancreatitis. Pancreas 2017, 46: 770-775. PMID: 28609365, DOI: 10.1097/mpa.0000000000000829.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomarkersCross-Over StudiesEndoscopes, GastrointestinalEndoscopy, GastrointestinalEndosonographyFeasibility StudiesFemaleHumansMaleMiddle AgedPancreatic Function TestsPancreatic JuicePancreatitis, ChronicPredictive Value of TestsPrognosisProspective StudiesReproducibility of ResultsSecretinTime FactorsWorkflowConceptsChronic pancreatitisPeak bicarbonate concentrationPancreatic function testsEndoscopic ultrasonographyFunction testsPoor concordanceProspective crossover studyPancreatic function testingFunctional testsBicarbonate concentrationPeak bicarbonateSecretin testingCrossover studyFunction testingTest concordanceDiscordant findingsFunctional assessmentPatientsImproved concordancePancreatitisSignificant correlationUltrasonographyConcordanceFeasible testCutoff
2016
The Use of Standard Gastrointestinal Endoscopic Ultrasound to Assess Cardiac Anatomy
Sentissi K, Sawhney M, Pleskow D, Sepe P, Mella J, Kwittken B, Ketwaroo G, Subramaniam B. The Use of Standard Gastrointestinal Endoscopic Ultrasound to Assess Cardiac Anatomy. Anesthesia & Analgesia 2016, 123: 547-550. PMID: 27541718, DOI: 10.1213/ane.0000000000001380.Peer-Reviewed Original ResearchConceptsVentricular functionAortic valveMitral valveRight ventricular systolic functionLinear echoendoscopeCardiovascular Anesthesiologists guidelinesEchocardiography/SocietyDepressed ventricular functionProspective observational studyVentricular systolic functionTransesophageal echocardiography examinationStandard clinical indicationsAcademic medical centerEarly diagnostic toolFormal echocardiographyPericardial effusionSystolic functionAortic dissectionAortic stenosisPulmonic valveTricuspid valveEchocardiography examinationAtrial appendageCardiac assessmentClinical indications
2015
High Glasgow Blatchford Score at admission is associated with recurrent bleeding after discharge for patients hospitalized with upper gastrointestinal bleeding
Sengupta N, Tapper E, Patwardhan V, Ketwaroo G, Thaker A, Leffler D, Feuerstein J. High Glasgow Blatchford Score at admission is associated with recurrent bleeding after discharge for patients hospitalized with upper gastrointestinal bleeding. Endoscopy 2015, 48: 9-15. PMID: 26340604, DOI: 10.1055/s-0034-1392651.Peer-Reviewed Original ResearchConceptsGlasgow-Blatchford scoreUpper gastrointestinal bleedingGBS scoresBlatchford scoreGastrointestinal bleedingMultivariable analysisEndoscopic interventionHigh riskIntensive care unit admissionCare unit admissionMultivariable Cox regressionPost-discharge outcomesGBS patientsUnit admissionCause readmissionHospital deathRecurrent bleedingCohort studyReadmission ratesConsecutive patientsHospital readmissionSignificant morbidityCox regressionPatientsReadmissionRisk Factors for Adverse Outcomes in Patients Hospitalized With Lower Gastrointestinal Bleeding
Sengupta N, Tapper E, Patwardhan V, Ketwaroo G, Thaker A, Leffler D, Feuerstein J. Risk Factors for Adverse Outcomes in Patients Hospitalized With Lower Gastrointestinal Bleeding. Mayo Clinic Proceedings 2015, 90: 1021-1029. PMID: 26141075, PMCID: PMC4770256, DOI: 10.1016/j.mayocp.2015.04.024.Peer-Reviewed Original ResearchConceptsRecurrent lower gastrointestinal bleedingLower gastrointestinal bleedingCharlson Comorbidity Index scoreComorbidity Index scoreActive malignancyRisk factorsGastrointestinal bleedingAdverse outcomesMultivariable Cox proportional hazards regression modelsHigher Charlson Comorbidity Index scoresIndex scoreCox proportional hazards regression modelProportional hazards regression modelsBeth Israel Deaconess Medical CenterProspective observational studyHazards regression modelsAssociation of variablesRecurrent bleedingHospital dischargeConsecutive patientsHospital readmissionObservational studyMedical CenterMortality riskPatients
2014
The Risks of Thromboembolism Vs. Recurrent Gastrointestinal Bleeding after Interruption of Systemic Anticoagulation in Hospitalized Inpatients With Gastrointestinal Bleeding: A Prospective Study
Sengupta N, Feuerstein J, Patwardhan V, Tapper E, Ketwaroo G, Thaker A, Leffler D. The Risks of Thromboembolism Vs. Recurrent Gastrointestinal Bleeding after Interruption of Systemic Anticoagulation in Hospitalized Inpatients With Gastrointestinal Bleeding: A Prospective Study. The American Journal Of Gastroenterology 2014, 110: 328. PMID: 25512338, DOI: 10.1038/ajg.2014.398.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnticoagulantsBenzimidazolesBeta-AlanineCohort StudiesDabigatranEnoxaparinFemaleGastrointestinal HemorrhageHeparinHumansIschemic Attack, TransientLongitudinal StudiesMaleMiddle AgedMorpholinesPatient ReadmissionProspective StudiesPulmonary EmbolismPyrazolesPyridonesRecurrenceRivaroxabanStrokeThiophenesThromboembolismVenous ThrombosisWarfarinWithholding TreatmentConceptsRecurrent gastrointestinal bleedingGastrointestinal bleedingSystemic anticoagulationAnticoagulation continuationThromboembolic eventsThrombotic eventsEtiology of GIBProspective observational cohort studyIntensive care unit careHospital transfusion requirementsMajor thrombotic episodesRisk of continuationObservational cohort studyRisk of thromboembolismCox proportional hazardsTransfusion requirementsCohort studyHospital dischargeUnit careConsecutive patientsHospital readmissionThrombotic episodesProspective studyHospitalized inpatientsFollowing outcomes