Reduced microstructural integrity of the white matter underlying anterior cingulate cortex is associated with increased saccadic latency in schizophrenia
Manoach D, Ketwaroo G, Polli F, Thakkar K, Barton J, Goff D, Fischl B, Vangel M, Tuch D. Reduced microstructural integrity of the white matter underlying anterior cingulate cortex is associated with increased saccadic latency in schizophrenia. NeuroImage 2007, 37: 599-610. PMID: 17590354, DOI: 10.1016/j.neuroimage.2007.04.062.Peer-Reviewed Original ResearchConceptsAnterior cingulate cortexDiffusion tensor imagingWhite matterVolitional saccadesCingulate cortexFractional anisotropySaccadic latencyMicrostructural integrityLonger saccadic latenciesRight hemisphereCingulate white matterWhite matter abnormalitiesAnterior cingulum bundleOcular motor controlFrontal eye fieldMedicated schizophrenia outpatientsSaccadic eye movementsPosterior parietal cortexInter-individual variabilityMedicated schizophreniaHealthy controlsProlonged latencyCortical componentsSurface-based coordinate systemEye field