Intakes of caffeine, coffee and tea and risk of amyotrophic lateral sclerosis: Results from five cohort studies
Fondell E, O’Reilly É, Fitzgerald KC, Falcone GJ, Kolonel LN, Park Y, Gapstur SM, Ascherio A. Intakes of caffeine, coffee and tea and risk of amyotrophic lateral sclerosis: Results from five cohort studies. Amyotrophic Lateral Sclerosis And Frontotemporal Degeneration 2015, 16: 366-371. PMID: 25822002, PMCID: PMC4589421, DOI: 10.3109/21678421.2015.1020813.Peer-Reviewed Original ResearchConceptsAmyotrophic lateral sclerosisMultivariable-adjusted risk ratiosALS riskRisk ratioCohort studyLateral sclerosisCases of ALSCox proportional hazards regressionProportional hazards regressionLarge cohort studyIntake of caffeineAdenosine A2A receptorsRandom-effects modelConsumption of caffeineHazards regressionALS incidenceLowest quintileMotor neuronsCaffeine intakeA2A receptorsAssociation of caffeineLarger studyIntakeSclerosisRisk