2014
Dietary ω-3 Polyunsaturated Fatty Acid Intake and Risk for Amyotrophic Lateral Sclerosis
Fitzgerald KC, O’Reilly É, Falcone GJ, McCullough ML, Park Y, Kolonel LN, Ascherio A. Dietary ω-3 Polyunsaturated Fatty Acid Intake and Risk for Amyotrophic Lateral Sclerosis. JAMA Neurology 2014, 71: 1102-1110. PMID: 25023276, PMCID: PMC4160351, DOI: 10.1001/jamaneurol.2014.1214.Peer-Reviewed Original ResearchConceptsAmyotrophic lateral sclerosisMultivariable-adjusted risk ratiosALS riskRisk ratioHealth StudyLateral sclerosisCancer Prevention Study II Nutrition CohortPolyunsaturated Fatty Acid IntakeCox proportional hazards regressionOnset of ALSHealth Professionals FollowHealth-AARP DietNurses' Health StudyFood frequency questionnaireFatty acid intakeSevere progressive diseaseProportional hazards regressionMultiethnic Cohort StudyRandom-effects methodDietary ωNutrition CohortProfessionals FollowCohort studyFrequency questionnaireProgressive disease
2013
Early-Onset Alopecia and Amyotrophic Lateral Sclerosis: A Cohort Study
Fondell E, Fitzgerald KC, Falcone GJ, O'Reilly É, Ascherio A. Early-Onset Alopecia and Amyotrophic Lateral Sclerosis: A Cohort Study. American Journal Of Epidemiology 2013, 178: 1146-1149. PMID: 23942216, PMCID: PMC3783095, DOI: 10.1093/aje/kwt096.Peer-Reviewed Original ResearchConceptsAge 45 yearsEarly-onset alopeciaRisk of ALSExtensive alopeciaTAR DNA-binding protein 43DNA-binding protein 43Health Professionals FollowAmyotrophic lateral sclerosisEarly baldingProfessionals FollowCohort studyModerate alopeciaProtein 43Large cohortHigh riskLateral sclerosisUS menAlopeciaSingle nucleotide polymorphism (SNP) variantsPolymorphism variantsALSMenFurther investigationRiskBaldingIntakes of vitamin C and carotenoids and risk of amyotrophic lateral sclerosis: Pooled results from 5 cohort studies
Fitzgerald KC, O'Reilly ÉJ, Fondell E, Falcone GJ, McCullough ML, Park Y, Kolonel LN, Ascherio A. Intakes of vitamin C and carotenoids and risk of amyotrophic lateral sclerosis: Pooled results from 5 cohort studies. Annals Of Neurology 2013, 73: 236-245. PMID: 23362045, PMCID: PMC3608702, DOI: 10.1002/ana.23820.Peer-Reviewed Original ResearchConceptsRisk of ALSAmyotrophic lateral sclerosisNurses' Health StudyRisk ratioALS deathsVitamin CLateral sclerosisHealth StudyCancer Prevention Study II Nutrition CohortCox proportional hazards regressionMultivariate risk ratiosRetired Persons DietHealth Professionals FollowVitamin C intakeNational Death IndexProportional hazards regressionHigh dietary intakeRandom-effects methodNutrition CohortProfessionals FollowCohort studyProspective cohortC intakeDeath IndexHazards regression