Interrelationship of superficial siderosis and microbleeds in cerebral amyloid angiopathy
Shoamanesh A, Martinez-Ramirez S, Oliveira-Filho J, Reijmer Y, Falcone GJ, Ayres A, Schwab K, Goldstein JN, Rosand J, Gurol ME, Viswanathan A, Greenberg SM. Interrelationship of superficial siderosis and microbleeds in cerebral amyloid angiopathy. Neurology 2014, 83: 1838-1843. PMID: 25320098, PMCID: PMC4240429, DOI: 10.1212/wnl.0000000000000984.Peer-Reviewed Original ResearchConceptsCortical superficial siderosisCerebral amyloid angiopathyCMB countCerebral microbleedsSuperficial siderosisAmyloid angiopathyΕ4 allele frequencyCross-sectional analysisCSS presenceAPOE genotypeAPOE ε4MRI scansAngiopathyMicrobleedsSiderosisCountSeverityGenetic associationLongitudinal research studyCS relativeDistinct patternsAllele frequenciesSubjectsIndividualsTertile