Principle of rational prescribing and deprescribing in older adults with multiple chronic conditions
Ouellet GM, Ouellet JA, Tinetti ME. Principle of rational prescribing and deprescribing in older adults with multiple chronic conditions. Therapeutic Advances In Drug Safety 2018, 9: 639-652. PMID: 30479739, PMCID: PMC6243421, DOI: 10.1177/2042098618791371.Peer-Reviewed Original ResearchMultiple chronic conditionsOptimal treatment regimensTreatment regimensOlder adultsChronic conditionsClinical trajectoriesMedication-related harmPatient's own prioritiesPatient's clinical trajectoryOptimal prescribingTherapeutic trialsPrescribed medicationsClinical statusHealth outcome goalsHealthy patientsRational prescribingPatient goalsClinical trialsPatient prioritiesPatientsSignificant burdenRegimensAdverse effectsAdultsLess benefit