Enlarged pituitary gland volume: a possible state rather than trait marker of psychotic disorders.
Guimond S, Alftieh A, Devenyi G, Mike L, Chakravarty M, Shah J, Parker D, Sweeney J, Pearlson G, Clementz B, Tamminga C, Keshavan M. Enlarged pituitary gland volume: a possible state rather than trait marker of psychotic disorders. Psychological Medicine 2024, 54: 1835-1843. PMID: 38357733, PMCID: PMC11132920, DOI: 10.1017/s003329172300380x.Peer-Reviewed Original ResearchPituitary gland volumePsychotic disordersSymptom severityAntipsychotic doseIllness durationCognitive functionAssociated with greater symptom severitySignificant effect of diagnosisAssociated with symptom severityHigher antipsychotic dosePituitary volumeBipolar-Schizophrenia NetworkIntermediate Phenotypes consortiumStructural magnetic resonance imagingProgression of psychosisGreater symptom severityEffect of diagnosisLower cognitive functionMore severe symptomsSample of individualsTransdiagnostic sampleMAGeT Brain algorithmGland volumeTrait markerBetween-group differences