2023
Peripheral inflammatory subgroup differences in anterior Default Mode network and multiplex functional network topology are associated with cognition in psychosis
Lizano P, Kiely C, Mijalkov M, Meda S, Keedy S, Hoang D, Zeng V, Lutz O, Pereira J, Ivleva E, Volpe G, Xu Y, Lee A, Rubin L, Hill S, Clementz B, Tamminga C, Pearlson G, Sweeney J, Gershon E, Keshavan M, Bishop J. Peripheral inflammatory subgroup differences in anterior Default Mode network and multiplex functional network topology are associated with cognition in psychosis. Brain Behavior And Immunity 2023, 114: 3-15. PMID: 37506949, PMCID: PMC10592140, DOI: 10.1016/j.bbi.2023.07.014.Peer-Reviewed Original ResearchConceptsResting-state networksHealthy controlsInter-network connectivityWorse verbal fluencyAnterior default mode networkC-reactive proteinResting-state functional networksDefault mode network connectivityRight frontoparietal networkMode network connectivityWorse cognitive performanceResting-state fMRIDefault mode networkFunctional network topologyInflammatory signatureSystemic inflammationInflammatory subgroupIL-6Neuroanatomical alterationsPsychosis probandsCo-activation patternsPsychosis spectrum disordersNetwork dysfunctionMultiple comparison correctionClinical implications
2021
Anterior Default Mode Network Mediates the Relationship Between Systemic Inflammation and Cognition in Idiopathic Psychosis
Lizano P, Keedy S, Meda S, Hill K, Lee A, Lutz O, Rubin L, Tamminga C, Clementz B, Pearlson G, Gershon E, Sweeney J, Keshavan M, Bishop J. Anterior Default Mode Network Mediates the Relationship Between Systemic Inflammation and Cognition in Idiopathic Psychosis. Biological Psychiatry 2021, 89: s259. DOI: 10.1016/j.biopsych.2021.02.648.Peer-Reviewed Original Research