Functionalization at position 3 of the phenyl ring of the potent mGluR5 noncompetitive antagonists MPEP
Alagille D, Baldwin R, Roth B, Wroblewski J, Grajkowska E, Tamagnan G. Functionalization at position 3 of the phenyl ring of the potent mGluR5 noncompetitive antagonists MPEP. Bioorganic & Medicinal Chemistry Letters 2005, 15: 945-949. PMID: 15686891, DOI: 10.1016/j.bmcl.2004.12.047.Peer-Reviewed Original ResearchAnimalsInhibitory Concentration 50MicePyridinesReceptors, Kainic AcidStructure-Activity Relationship