2014
Role of medullary progenitor cells in epithelial cell migration and proliferation
Chen D, Chen Z, Zhang Y, Park C, Al-Omari A, Moeckel GW. Role of medullary progenitor cells in epithelial cell migration and proliferation. American Journal Of Physiology. Renal Physiology 2014, 307: f64-f74. PMID: 24808539, PMCID: PMC4080159, DOI: 10.1152/ajprenal.00547.2013.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DifferentiationCell MovementCell ProliferationCells, CulturedEpithelial CellsMesenchymal Stem CellsMiceReceptors, CXCRStem CellsConceptsProgenitor cellsEpithelial cell migrationSide populationInterstitial cell lineEpithelial cellsBone marrow-derived stem cellsCell migrationMarrow-derived stem cellsInjury repairMedullary interstitiumDuct cellsInner medullaCell proliferationCell linesProliferationTubule formationStem cellsInterstitial progenitor cellsDifferentiation mediumCellsPhenotypic characteristicsCritical roleIMCD3 cellsPGE2CXCR4
2013
Early B-cell factor 1 is an essential transcription factor for postnatal glomerular maturation
Fretz JA, Nelson T, Velazquez H, Xi Y, Moeckel GW, Horowitz MC. Early B-cell factor 1 is an essential transcription factor for postnatal glomerular maturation. Kidney International 2013, 85: 1091-1102. PMID: 24172684, PMCID: PMC4006322, DOI: 10.1038/ki.2013.433.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAlbuminuriaAnimalsBlood Urea NitrogenCell DifferentiationCells, CulturedGene Expression Regulation, DevelopmentalGenotypeGlomerular Filtration RateKidney GlomerulusMice, 129 StrainMice, Inbred C57BLMice, KnockoutOrganogenesisPhenotypePodocytesSignal TransductionTime FactorsTrans-ActivatorsVascular Endothelial Growth Factor AConceptsEarly B-cell factor 1B cell factor 1Transcription factorsNovel roleTranscription factor early B cell factor 1Expression of Ebf1Essential transcription factorFactor 1Podocyte maturationMesenchymal progenitorsB cell maturationProper maturationBlood urea nitrogen levelsElevated blood urea nitrogen levelsWild-type control miceGlomerular filtration rateVascular endothelial growth factor AGlomerular maturationUrea nitrogen levelsGrowth factor ARenal developmentEBF1Factor AGlomerular developmentNephron maturation