Importance of Functional EGF Receptors in Recovery from Acute Nephrotoxic Injury
Wang Z, Chen JK, Wang SW, Moeckel G, Harris RC. Importance of Functional EGF Receptors in Recovery from Acute Nephrotoxic Injury. Journal Of The American Society Of Nephrology 2003, 14: 3147-3154. PMID: 14638913, DOI: 10.1097/01.asn.0000098681.56240.1a.Peer-Reviewed Original ResearchConceptsAcute nephrotoxic injuryTubular injuryNephrotoxic injurySerum blood urea nitrogenEGF receptorDUTP nick end labeling stainingNick end labeling stainingRenal tubular injuryBlood urea nitrogenWild-type miceReceptor tyrosine kinase activityTubule injuryRenal compromiseCreatinine levelsRenal expressionAcute injuryHistologic evidenceExogenous administrationSuch injuriesLabeling stainingKidney's abilityUrea nitrogenRate of recoveryInjuryMice