Kidney-targeted liposome-mediated gene transfer in mice
Lai L, Moeckel G, Lien Y. Kidney-targeted liposome-mediated gene transfer in mice. Gene Therapy 1997, 4: 426-431. PMID: 9274719, DOI: 10.1038/sj.gt.3300406.Peer-Reviewed Original ResearchConceptsBlood urea nitrogen levelsUrea nitrogen levelsRenal tubular cellsTubular epithelial cellsGene therapyRenal histologyLeft kidneyArterial injectionArterial groupParenchymal groupTubular cellsGene transferParenchymal injectionOuter medullaD-galactopyranoside stainingKidneyEpithelial cellsInterstitial compartmentCytomegalovirus immediate-early gene promoterInjectionLiposome-mediated gene deliveryTherapyΒ-galactosidase expressionTransient gene transferImmediate-early gene promoter