2000
Genetically and epidemiologically related “non‐syncytium‐inducing” isolates of HIV‐1 display heterogeneous growth patterns in macrophages
Jesus M, Anders C, Miller G, Sleasman J, Goodenow M, Andiman W. Genetically and epidemiologically related “non‐syncytium‐inducing” isolates of HIV‐1 display heterogeneous growth patterns in macrophages. Journal Of Medical Virology 2000, 61: 171-180. PMID: 10797371, DOI: 10.1002/(sici)1096-9071(200006)61:2<171::aid-jmv1>3.0.co;2-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmino Acid SequenceAntigens, ViralCD4 AntigensCell LineCells, CulturedChild, PreschoolFemaleGiant CellsHIV Core Protein p24HIV InfectionsHIV-1HumansInfantLeukocytes, MononuclearMacrophagesMolecular Sequence DataPhenotypeProspective StudiesProtein Structure, TertiaryReceptors, ChemokineTransfectionTropismU937 CellsViral ProteinsVirus ReplicationConceptsNSI virusesDisease stageSurrogate markerPediatric human immunodeficiency virus type 1 (HIV-1) infectionHuman immunodeficiency virus type 1 (HIV-1) infectionVirus type 1 infectionCell linesCo-receptor preferenceM-tropic virusesType 1 infectionT-cell tropicDual tropicInducing (NSI) virusesNSI isolatesAsymptomatic childrenMacrophage-tropicClinical progressionSymptomatic childrenV3 loopNSI phenotypeHIV-1Lymphotropic virusCategory A1Heterogeneous growth patternsGenetic featuresDihydrofolate Reductase from Kaposi's Sarcoma-Associated Herpesvirus
Cinquina C, Grogan E, Sun R, Lin S, Beardsley G, Miller G. Dihydrofolate Reductase from Kaposi's Sarcoma-Associated Herpesvirus. Virology 2000, 268: 201-217. PMID: 10683342, DOI: 10.1006/viro.1999.0165.Peer-Reviewed Original ResearchConceptsKaposi's sarcoma-associated herpesvirusSarcoma-associated herpesvirusDihydrofolate reductaseEarly lytic cycle genesNucleotide metabolism genesDHFR activityHuman DHFRViral enzymesPrimary effusion lymphomaLytic cycle genesKSHV lytic cycleMethionine biosynthesisCycle genesHuman dihydrofolate reductaseCultured B-cell linesMetabolism genesPEL cell linesOwn enzymesB cell linesAmino acidsPEL cellsChemical inductionLytic cycleE. coliInfected cells
1999
Kaposi’s Sarcoma-Associated Herpesvirus Encodes a bZIP Protein with Homology to BZLF1 of Epstein-Barr Virus
Lin S, Robinson D, Miller G, Kung H. Kaposi’s Sarcoma-Associated Herpesvirus Encodes a bZIP Protein with Homology to BZLF1 of Epstein-Barr Virus. Journal Of Virology 1999, 73: 1909-1917. PMID: 9971770, PMCID: PMC104432, DOI: 10.1128/jvi.73.3.1909-1917.1999.Peer-Reviewed Original Research
1998
A viral gene that activates lytic cycle expression of Kaposi’s sarcoma-associated herpesvirus
Sun R, Lin S, Gradoville L, Yuan Y, Zhu F, Miller G. A viral gene that activates lytic cycle expression of Kaposi’s sarcoma-associated herpesvirus. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 10866-10871. PMID: 9724796, PMCID: PMC27987, DOI: 10.1073/pnas.95.18.10866.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBase SequenceCloning, MolecularDNA PrimersDNA, ComplementaryGene Expression Regulation, NeoplasticGenes, ViralHerpesvirus 4, HumanHerpesvirus 8, HumanHumansMolecular Sequence DataSarcoma, KaposiSequence Homology, Amino AcidTranscription, GeneticTumor Cells, CulturedVirus ActivationConceptsEpstein-Barr virusKaposi's sarcoma-associated herpesvirusSarcoma-associated herpesvirusSmall viral capsid antigenPathogenesis of KSHVLytic cycle gene expressionViral capsid antigenLatent viral genomeCapsid antigenLytic cycle genesInterleukin-6Immediate early genesViral cytokineEarly lytic genesLytic genesHerpesvirusVirusViral genesViral genomeExpressionGene expressionCytokinesPathogenesisCycle genesGenes
1995
Transmissible Retrovirus in Epstein-Burr Virus-Producer B95-8 Cells
Sun R, Grogan E, Shedd D, Bykovsky A, Kushnaryov V, Grossberg S, Miller G. Transmissible Retrovirus in Epstein-Burr Virus-Producer B95-8 Cells. Virology 1995, 209: 374-383. PMID: 7778272, DOI: 10.1006/viro.1995.1269.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBetaretrovirusB-LymphocytesCallithrixCell LineCloning, MolecularDNA PrimersDNA, ComplementaryGene LibraryGene Products, gagGenes, gagHerpesvirus 4, HumanHumansMicroscopy, ElectronMolecular Sequence DataPolymerase Chain ReactionRepetitive Sequences, Nucleic AcidSaimiriT-LymphocytesVirus ReplicationConceptsEpstein-Barr virusB95-8 cellsAbsence of EBVCell linesB95-8 isolateB95-8 strainMarmoset cell linesHuman lymphoid cell linesT cell linesLymphoid cell linesType D retrovirusHuman BLymphocyte immortalizationInfectious virusViral replicationHuman isolatesGag regionBiologic propertiesTransmissible retrovirusUltrastructural appearanceD retrovirusesAmino acid changesVirusSMRVGag sequences
1988
Polymorphisms of the region of the Epstein-Barr virus genome which disrupts latency
Jenson H, Miller G. Polymorphisms of the region of the Epstein-Barr virus genome which disrupts latency. Virology 1988, 165: 549-564. PMID: 2841800, DOI: 10.1016/0042-6822(88)90599-5.Peer-Reviewed Original Research