2000
Genetically and epidemiologically related “non‐syncytium‐inducing” isolates of HIV‐1 display heterogeneous growth patterns in macrophages
Jesus M, Anders C, Miller G, Sleasman J, Goodenow M, Andiman W. Genetically and epidemiologically related “non‐syncytium‐inducing” isolates of HIV‐1 display heterogeneous growth patterns in macrophages. Journal Of Medical Virology 2000, 61: 171-180. PMID: 10797371, DOI: 10.1002/(sici)1096-9071(200006)61:2<171::aid-jmv1>3.0.co;2-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmino Acid SequenceAntigens, ViralCD4 AntigensCell LineCells, CulturedChild, PreschoolFemaleGiant CellsHIV Core Protein p24HIV InfectionsHIV-1HumansInfantLeukocytes, MononuclearMacrophagesMolecular Sequence DataPhenotypeProspective StudiesProtein Structure, TertiaryReceptors, ChemokineTransfectionTropismU937 CellsViral ProteinsVirus ReplicationConceptsNSI virusesDisease stageSurrogate markerPediatric human immunodeficiency virus type 1 (HIV-1) infectionHuman immunodeficiency virus type 1 (HIV-1) infectionVirus type 1 infectionCell linesCo-receptor preferenceM-tropic virusesType 1 infectionT-cell tropicDual tropicInducing (NSI) virusesNSI isolatesAsymptomatic childrenMacrophage-tropicClinical progressionSymptomatic childrenV3 loopNSI phenotypeHIV-1Lymphotropic virusCategory A1Heterogeneous growth patternsGenetic features
1993
Quantitative leukoviremia and immune complex-dissociated antigenemia as predictors of infection status in children born to mothers infected with human immunodeficiency virus type 1
Ikeda M, Andiman W, Mezger J, Shapiro E, Miller G. Quantitative leukoviremia and immune complex-dissociated antigenemia as predictors of infection status in children born to mothers infected with human immunodeficiency virus type 1. The Journal Of Pediatrics 1993, 122: 524-531. PMID: 8463895, DOI: 10.1016/s0022-3476(05)83530-9.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus type 1Immunodeficiency virus type 1Virus type 1Infection statusCulture resultsHIV-1-infected mothersType 1Peripheral blood mononuclear cellsSerum antigen testHIV-1 antigensBlood mononuclear cellsPositive culture resultsNegative culture resultsSeronegative donorsInfected childrenReactive antibodiesAntigen testMononuclear cellsClinical criteriaHIV-1Immune complexesCocultureChildrenPositive resultsAntigen
1991
Relation between HIV-1 syncytium inhibition antibodies and clinical outcome in children
Brenner TJ, Dahl KE, Miller G, Andiman W, Andiman WA, Olson B, Miller G, Andiman W, Miller G. Relation between HIV-1 syncytium inhibition antibodies and clinical outcome in children. The Lancet 1991, 337: 1001-1005. PMID: 1673167, DOI: 10.1016/0140-6736(91)92660-t.Peer-Reviewed Original ResearchConceptsLymphocytic interstitial pneumonitisOpportunistic infectionsClinical outcomesSyncytium formationCD4 receptorHIV-1-infected mothersWestern blotHIV-1 infected cellsInterstitial pneumonitisInhibition antibodiesHIV-1Giant cellsIndicator cellsAntibodiesInfected cellsTitresChildrenCell linesCell spreadSerumReceptorsOutcomesVirusCellsPneumonitis