1997
The Nicolas Andry Award-1995 Fracture Healing; Radiation Induced Alterations
Pelker R, Friedlaender G. The Nicolas Andry Award-1995 Fracture Healing; Radiation Induced Alterations. Clinical Orthopaedics And Related Research® 1997, 341: 267-282. PMID: 9269183, DOI: 10.1097/00003086-199708000-00038.Peer-Reviewed Original ResearchConceptsIncidence of fracturesNonunion of fracturesDose fractionation schemesRadiation-Induced AlterationsNicolas Andry AwardSingle doseFractionation schemeClinical observationsAllogeneic boneFracture healingIrradiated boneControl groupFinal repairIncidenceInduced alterationsRat femur modelNonunionDegree of delayFracturesImmature levelBoneRepairEffects of radiationAnimalsRefracture
1991
Induction of specific T-cell responsiveness to allogeneic bone.
Horowitz M, Friedlaender G. Induction of specific T-cell responsiveness to allogeneic bone. Journal Of Bone And Joint Surgery 1991, 73: 1157-68. PMID: 1716256, DOI: 10.2106/00004623-199173080-00004.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, Differentiation, T-LymphocyteBone and BonesBone MarrowBone TransplantationCells, CulturedCytotoxicity Tests, ImmunologicEpitopesLymphocyte ActivationLymphocyte Culture Test, MixedMajor Histocompatibility ComplexMiceMice, Inbred StrainsT-LymphocytesTransplantation, HomologousTransplantation, IsogeneicConceptsT cellsAllogeneic boneMajor histocompatibility complexHistocompatibility complexAlloreactive T cellsClass II determinantsPurified T cellsSpecific immune responseT cell responsivenessMixed lymphocyte cultureCell surface phenotypeStrains of miceBone marrow cellsState of activationStimulating antigenImmune responseBone donorsAntigen specificityBone marrowLymphocyte culturesSecondary exposurePrimed cellsResponding cellsAntigenBone
1989
Allograft incorporation: A biomechanical evaluation in a rat model
Pelker R, McKay J, Troiano N, Panjabi M, Friedlaender G. Allograft incorporation: A biomechanical evaluation in a rat model. Journal Of Orthopaedic Research® 1989, 7: 585-589. PMID: 2786956, DOI: 10.1002/jor.1100070417.Peer-Reviewed Original ResearchConceptsLewis ratsLevel of freezingImmunologic responseSprague-Dawley rat femursRat modelImmune responseAllogeneic boneFresh allograftsOsteosynthesis siteBiomechanical evaluationBiomechanical testingBiologic responseSubsequent healingAllograftsRat femurRatsIntact boneBoneFemurSignificant levelsResponseTransplantationTransplantGraftWeeks
1987
Allogeneic Bone in the Treatment of Tumors, Trauma, and Congenital Anomalies of the Hand
Trumble T, Friedlaender G. Allogeneic Bone in the Treatment of Tumors, Trauma, and Congenital Anomalies of the Hand. Orthopedic Clinics Of North America 1987, 18: 301-310. PMID: 3550577, DOI: 10.1016/s0030-5898(20)30393-x.Peer-Reviewed Original ResearchConceptsAllogeneic boneBone graftEarly motionAutogenous corticocancellous graftCongruent joint surfaceLarge osteochondral allograftsShorter hospital stayDonor site deficitMassive bone graftGraft donor sitesTubular graftSmall bone graftStrong cortical boneDonor siteAutogenous bone graftDonor site morbidityTreatment of tumorsHospital stayCortical graftsPediatric patientsFibular headHand therapyCorticocancellous graftHand injuriesInternal fixation
1983
FROZEN AND FREEZE-DRIED BONE GRAFTS
PELKER R, FRIEDLAENDER G, MARKHAM T. FROZEN AND FREEZE-DRIED BONE GRAFTS. Clinical Orthopaedics And Related Research® 1983, 174: 36-42. PMID: 6339142, DOI: 10.1097/00003086-198304000-00007.Peer-Reviewed Original Research