2005
Mechanistic Comparisons Between Photosystem II and Cytochrome c Oxidase
Brudvig G, Wikström M. Mechanistic Comparisons Between Photosystem II and Cytochrome c Oxidase. Advances In Photosynthesis And Respiration 2005, 22: 697-713. DOI: 10.1007/1-4020-4254-x_32.Peer-Reviewed Original ResearchFour-electron reductionSingle reaction stepSame chemical reactionPhotosystem IIRole of protonsOxygen reductionProton transferMolecular oxygenReaction mechanismReaction stepsActive siteWater reactionChemical reactionsRequirement of electronsMechanistic comparisonReverse reactionReactionCytochrome c oxidaseProtonsC oxidaseMechanistic similaritiesChemistryElectronsWaterRespiratory enzymes
1984
Electron spin relaxation of CuA and cytochrome a in cytochrome c oxidase. Comparison to heme, copper, and sulfur radical complexes.
Brudvig G, Blair D, Chan S. Electron spin relaxation of CuA and cytochrome a in cytochrome c oxidase. Comparison to heme, copper, and sulfur radical complexes. Journal Of Biological Chemistry 1984, 259: 11001-11009. PMID: 6088526, DOI: 10.1016/s0021-9258(18)90613-7.Peer-Reviewed Original ResearchConceptsType 1 copperType 2 copperSulfur radicalsBlue copper proteinsMetal centerCopper complexesRadical complexesCopper centerCO complexCopper proteinsProtein environmentLow-spin heme proteinsParamagnetic sitesSpin centersHeme proteinsInorganic copperMagnetic dipolar interactionElectron spin relaxationCopperComplexesSpin-lattice relaxationDipolar interactionsCytochrome c oxidaseRadicalsCuA
1983
The metal centers of cytochrome c oxidase: Structure and function
Chan S, Blair D, Martin C, Wang H, Gelles J, Morgan J, Witt S, Birge R, Stevens T, Brudvig G. The metal centers of cytochrome c oxidase: Structure and function. Inorganica Chimica Acta 1983, 79: 72-73. DOI: 10.1016/s0020-1693(00)95101-6.Peer-Reviewed Original ResearchMetal centerTransmembrane electrochemical potential gradientDioxygen reductionElectron transferElectrochemical potential gradientDioxygen reduction reactionReduction of dioxygenUnambiguous structural informationProton pumpingEPR/ENDOR studyElectron transfer rate theoryOxygen reductionReduction reactionMetal sitesBiosynthetic procedureElectrochemical potential profilesFerryl intermediateENDOR studyReduction sitePotential gradientReaction originatesDioxygen reduction siteFree energyCytochrome c oxidaseStructural informationThe Structure of the Metal Centers in Cytochrome c Oxidase
Chan S, Martin C, Wang H, Brudvig G, Stevens T. The Structure of the Metal Centers in Cytochrome c Oxidase. Nato Science Series C: 1983, 313-328. DOI: 10.1007/978-94-009-7049-6_27.Peer-Reviewed Original ResearchMetal centerLow-temperature electron paramagnetic resonance (EPR) spectroscopyElectron nuclear double resonance spectroscopyNuclear double resonance spectroscopyElectron paramagnetic resonance spectroscopyResonance spectroscopyParamagnetic resonance spectroscopyLow-temperature EPRO2 reduction siteDouble resonance spectroscopyReduction siteSpectroscopyCytochrome c oxidaseC oxidaseUnambiguous informationStructureEPRAmino acidsOxidaseOxideElucidationAcidNitric oxide
1982
The nature of CuA in cytochrome c oxidase.
Stevens T, Martin C, Wang H, Brudvig G, Scholes C, Chan S. The nature of CuA in cytochrome c oxidase. Journal Of Biological Chemistry 1982, 257: 12106-12113. PMID: 6288707, DOI: 10.1016/s0021-9258(18)33685-8.Peer-Reviewed Original ResearchConceptsCytochrome c oxidaseYeast cytochrome c oxidaseC oxidaseCysteine sulfurProteinBeef heartOxidaseElectron nuclear double resonance (ENDOR) spectraElectron paramagnetic resonanceSubstantial spin densityParamagnetic resonanceDouble resonance spectraBetaCuAResonance spectraCysteineSpin densityHistidine
1980
Reactions of nitric oxide with cytochrome c oxidase.
Brudvig G, Stevens T, Chan S. Reactions of nitric oxide with cytochrome c oxidase. Biochemistry 1980, 19: 5275-85. PMID: 6255988, DOI: 10.1021/bi00564a020.Peer-Reviewed Original ResearchEvidence for the absence of photoreduction of the metal centers of cytochrome c oxidase by x-irradiation
Brudvig G, Bocian D, Gamble R, Chan S. Evidence for the absence of photoreduction of the metal centers of cytochrome c oxidase by x-irradiation. Biochimica Et Biophysica Acta 1980, 624: 78-89. PMID: 6250634, DOI: 10.1016/0005-2795(80)90227-5.Peer-Reviewed Original ResearchConceptsConventional X-ray sourceStanford Synchrotron Radiation LaboratoryX-ray absorption measurementsX-ray photonsPhotons/sX-ray fluxX-ray sourcesSynchrotron Radiation LaboratoryMetal centerOptical spectroscopyRadiation LaboratoryAbsorption measurementsElectron paramagnetic resonanceParamagnetic resonanceCytochrome c oxidasePhotonsPhotoreductionC oxidaseRadiationResonanceSpectroscopyOxidaseSourceMeasurementsFlux