2017
The antihypertensive effects of aerobic versus isometric handgrip resistance exercise
Ash GI, Taylor BA, Thompson PD, MacDonald HV, Lamberti L, Chen MH, Farinatti P, Kraemer WJ, Panza GA, Zaleski AL, Deshpande V, Ballard KD, Mujtaba M, White CM, Pescatello LS. The antihypertensive effects of aerobic versus isometric handgrip resistance exercise. Journal Of Hypertension 2017, 35: 291-299. PMID: 27861249, PMCID: PMC5713890, DOI: 10.1097/hjh.0000000000001176.Peer-Reviewed Original ResearchConceptsIHG trainingAntihypertensive effectBlood pressureAerobic exerciseResistance exerciseCarotid-femoral pulse wave velocityPulse wave velocity changesBP benefitPrimary exercise modalityAmbulatory BP monitorPulse wave velocityMiddle-aged adultsSubset of participantsAntihypertensive therapyAwake SBPIHG exerciseAcute exerciseExercise modalitiesAcute boutAerobic trainingBP monitorAwake hoursStudy participantsLimited evidenceSBP
2016
Glucocorticoid Receptor (NR3C1) Variants Associate with the Muscle Strength and Size Response to Resistance Training
Ash GI, Kostek MA, Lee H, Angelopoulos TJ, Clarkson PM, Gordon PM, Moyna NM, Visich PS, Zoeller RF, Price TB, Devaney JM, Gordish-Dressman H, Thompson PD, Hoffman EP, Pescatello LS. Glucocorticoid Receptor (NR3C1) Variants Associate with the Muscle Strength and Size Response to Resistance Training. PLOS ONE 2016, 11: e0148112. PMID: 26821164, PMCID: PMC4731199, DOI: 10.1371/journal.pone.0148112.Peer-Reviewed Original ResearchConceptsMaximum voluntary contractionResistance trainingMuscle strengthPost-resistance trainingGlucocorticoid receptor polymorphismsGreater relative sizeCortisol sensitivityReceptor polymorphismsNR3C1 polymorphismsVoluntary contractionAllele carriersCortisol actionMuscle responsesCortisol productionRT programIsometric strengthAA homozygotesG alleleT alleleVariant associatesBiceps sizeEuropean American adultsSex differencesMuscle tissueAssociation