FURIN variant associations with postexercise hypotension are intensity and race dependent
Cilhoroz BT, Schifano ED, Panza GA, Ash GI, Corso L, Chen M, Deshpande V, Zaleski A, Farinatti P, Santos LP, Taylor BA, O'Neill RJ, Thompson PD, Pescatello LS. FURIN variant associations with postexercise hypotension are intensity and race dependent. Physiological Reports 2019, 7: e13952. PMID: 30706700, PMCID: PMC6356167, DOI: 10.14814/phy2.13952.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBicyclingBlack or African AmericanBlood PressureCase-Control StudiesExerciseFemaleFurinGenetic Association StudiesGenetic Predisposition to DiseaseHumansHypertensionHypotensionMaleMiddle AgedObesityPhenotypePolymorphism, Single NucleotideRisk FactorsTime FactorsWhite PeopleYoung AdultConceptsPostexercise hypotensionSystolic BPDiastolic BPBlood pressure responseAmbulatory BP monitorBlood pressure regulationModerate-intensity cyclingRace-dependent associationsObese blacksAerobic exerciseBP measurementsBP monitorIntensity cyclingAwake hoursMmHgPressure regulationMinor alleleMerit further explorationPressure responseHypotensionHypertensionP-valueReceptor processingMultiple testing