2021
Accounting for quality improvement during the conduct of embedded pragmatic clinical trials within healthcare systems: NIH Collaboratory case studies
Tuzzio L, Meyers CM, Dember LM, Grudzen CR, Melnick ER, Staman KL, Huang SS, Richards J, DeBar L, Vazquez MA, Green BB, Coronado GD, Jarvik JG, Braciszewski J, Ho PM, Wells BL, James K, Toto R, D’Onofrio G, Volandes A, Kuklinski MR, Catalano RF, Sterling SA, Morse EF, Curtis L, Larson EB. Accounting for quality improvement during the conduct of embedded pragmatic clinical trials within healthcare systems: NIH Collaboratory case studies. Healthcare 2021, 8: 100432. PMID: 34175091, PMCID: PMC8900087, DOI: 10.1016/j.hjdsi.2020.100432.Peer-Reviewed Original ResearchMeSH KeywordsDelivery of Health CareDementiaHumansQuality ImprovementResearch DesignResearch PersonnelConceptsPragmatic clinical trialsQI initiativesHealthcare systemClinical trialsHigh-quality patient-centered careClinical practice guidelinesHigh-quality evidencePatient-centered careQuality of careQuality improvement activitiesPractice guidelinesRoutine collaborationHealth questionsHealth systemTrialsHealth system operationsConduct phaseCareStudy teamPublic healthInterventionImprovement activitiesEPCTs
2019
Implementation facilitation to promote emergency department-initiated buprenorphine for opioid use disorder: protocol for a hybrid type III effectiveness-implementation study (Project ED HEALTH)
D’Onofrio G, Edelman EJ, Hawk KF, Pantalon MV, Chawarski MC, Owens PH, Martel SH, VanVeldhuisen P, Oden N, Murphy SM, Huntley K, O’Connor P, Fiellin DA. Implementation facilitation to promote emergency department-initiated buprenorphine for opioid use disorder: protocol for a hybrid type III effectiveness-implementation study (Project ED HEALTH). Implementation Science 2019, 14: 48. PMID: 31064390, PMCID: PMC6505286, DOI: 10.1186/s13012-019-0891-5.Peer-Reviewed Original ResearchConceptsOpioid use disorderEmergency departmentImplementation facilitationCost-effectiveness analysisUse disordersPatient engagementEmergency department-initiated buprenorphineEffectiveness-implementation studyEvaluation periodOpioid agonist treatmentSoft tissue infectionsInjection drug useGeneral medical conditionsHealth Services frameworkClinical Trials NetworkAcademic emergency departmentRate of provisionIF interventionOngoing medicationED visitsTissue infectionsED patientsFacilitated referralAgonist treatmentED providers
2009
Study Designs and Evaluation Models for Emergency Department Public Health Research
Broderick KB, Ranney ML, Vaca FE, D’Onofrio G, Rothman RE, Rhodes KV, Becker B, Haukoos JS. Study Designs and Evaluation Models for Emergency Department Public Health Research. Academic Emergency Medicine 2009, 16: 1124-1131. PMID: 20053232, PMCID: PMC3082772, DOI: 10.1111/j.1553-2712.2009.00557.x.Peer-Reviewed Original ResearchConceptsPublic health researchHealth researchStudy designActual clinical practiceAcademic Emergency Medicine consensus conferencePublic health investigatorsEmergency departmentPublic health workConsensus conferenceMethodologic featuresClinical practiceHealth investigatorsHealth workPublic healthRigorous program evaluationProgram evaluationEDFuture investigationsParticipant selectionBreakout sessionsThoughtful consideration
2002
Preventive care in the emergency department: screening and brief intervention for alcohol problems in the emergency department: a systematic review.
D'Onofrio G, Degutis L. Preventive care in the emergency department: screening and brief intervention for alcohol problems in the emergency department: a systematic review. Academic Emergency Medicine 2002, 9: 627-38. PMID: 12045080, DOI: 10.1111/j.1553-2712.2002.tb02304.x.Peer-Reviewed Original ResearchConceptsEmergency departmentU.S. Preventive Services Task Force reportAlcohol-related problemsSystematic reviewMethodology of systematic reviewsMethodological scoring systemPrevention of mortalityPrimary outcome measureBrief interventionPreventive careIncreased referralsED-basedOutcome measuresTask Force ReportExplanatory pieceTeam membersCochrane LibraryPrimary articlesAlcohol problemsStudy populationClinical practiceDecreased consumptionInterventionCollege settingPublished criteria
1992
Sample size & selection criteria
Rathlev N, D'onofrio G, Fish S. Sample size & selection criteria. Annals Of Emergency Medicine 1992, 21: 344-345. PMID: 1536500, DOI: 10.1016/s0196-0644(05)80920-5.Peer-Reviewed Original Research