2022
Use of a Brief Negotiation Interview in the emergency department to reduce high‐risk alcohol use among older adults: A randomized trial
Shenvi CL, Wang Y, Revankar R, Phillips J, Bush M, Biese KJ, Aylward A, D'Onofrio G, Platts‐Mills T. Use of a Brief Negotiation Interview in the emergency department to reduce high‐risk alcohol use among older adults: A randomized trial. Journal Of The American College Of Emergency Physicians Open 2022, 3: e12651. PMID: 35156089, PMCID: PMC8828696, DOI: 10.1002/emp2.12651.Peer-Reviewed Original ResearchHigh-risk alcohol useBrief Negotiation InterviewEmergency departmentHigh-risk drinkersAlcohol usePrimary outcomeOlder adultsSingle academic emergency departmentAcademic emergency departmentNon-Hispanic whitesUsual careED visitsED patientsEligible individualsAlcohol abuseAlcohol consumptionFull criteriaAlcoholism definitionMonthsNational InstituteAdultsSignificant differencesPatientsSignificant reductionOutcomes
2010
Integrating Project ASSERT: A Screening, Intervention, and Referral to Treatment Program for Unhealthy Alcohol and Drug Use Into an Urban Emergency Department
D’Onofrio G, Degutis LC. Integrating Project ASSERT: A Screening, Intervention, and Referral to Treatment Program for Unhealthy Alcohol and Drug Use Into an Urban Emergency Department. Academic Emergency Medicine 2010, 17: 903-911. PMID: 20670330, DOI: 10.1111/j.1553-2712.2010.00824.x.Peer-Reviewed Original ResearchConceptsSpecialized treatment facilitiesBrief Negotiation InterviewHealth promotion advocatesDrug useTreatment programUnhealthy alcoholED patientsEmergency departmentPercent of patientsAdult ED patientsAlcohol/drug useUrban emergency departmentLow-risk drinkingGeneral Health QuestionnaireAlcoholism guidelinesReferral completionUrban EDFacilitated referralDirect admissionHealth QuestionnaireUnhealthy drinkingAlcohol abusePatientsSeverity of useAlcohol consumption
2009
Emergency Medicine Public Health Research Funded by Federal Agencies: Progress and Priorities
D’Onofrio G, Goldstein AB, Denisco RA, Hingson R, Heffelfinger JD, Post LA. Emergency Medicine Public Health Research Funded by Federal Agencies: Progress and Priorities. Academic Emergency Medicine 2009, 16: 1065-1071. PMID: 20053224, DOI: 10.1111/j.1553-2712.2009.00555.x.Peer-Reviewed Original ResearchConceptsEmergency medicineEmergency department visitsNational InstituteAcademic Emergency Medicine consensus conferenceDepartment of HealthDepartment visitsPublic health researchAlcohol abuseConsensus conferenceDisease controlDrug abuseMental healthHealth researchPublic healthMedical disciplinesHealthPrevention
1999
Lorazepam for the Prevention of Recurrent Seizures Related to Alcohol
D'Onofrio G, Rathlev N, Ulrich A, Fish S, Freedland E. Lorazepam for the Prevention of Recurrent Seizures Related to Alcohol. New England Journal Of Medicine 1999, 340: 915-919. PMID: 10094637, DOI: 10.1056/nejm199903253401203.Peer-Reviewed Original ResearchConceptsPlacebo groupRecurrent seizuresSecond seizureLorazepam groupEmergency departmentNormal salineAlcohol abusePrimary end pointDouble-blind studyChronic alcohol abuseYears of ageIntravenous lorazepamHospital dischargeConsecutive patientsGeneralized seizuresEntry criteriaCommon causePatientsSeizuresEnd pointLorazepamObservation periodSignificant reductionHospitalSaline
1994
The lack of efficacy of phenytoin in the prevention of recurrent alcohol-related seizures
Rathlev N, D'Onofrio G, Fish S, Harrison P, Bernstein E, Hossack R, Pickens L. The lack of efficacy of phenytoin in the prevention of recurrent alcohol-related seizures. Annals Of Emergency Medicine 1994, 23: 513-518. PMID: 8135426, DOI: 10.1016/s0196-0644(94)70070-2.Peer-Reviewed Original ResearchConceptsAlcohol-related seizuresSix-hour observation periodNormal saline placeboDouble-blind trialObservation periodConfidence intervalsLack of efficacyChronic alcohol abuseYears of ageChi 2 analysisPlacebo groupConsecutive adultsEligible subjectsPhenytoin groupSaline placeboGeneralized seizuresPhenytoin administrationSecond seizureEmergency departmentNormal salineRelative riskTeaching hospitalAlcohol abuseDrug AdministrationSeizures