2020
The real‐world impact of dosing of methadone and buprenorphine in retention on opioid agonist therapies in Ukraine
Farnum SO, Makarenko I, Madden L, Mazhnaya A, Marcus R, Prokhorova T, Bojko MJ, Rozanova J, Dvoriak S, Islam Z, Altice FL. The real‐world impact of dosing of methadone and buprenorphine in retention on opioid agonist therapies in Ukraine. Addiction 2020, 116: 83-93. PMID: 32428276, PMCID: PMC7674222, DOI: 10.1111/add.15115.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyOAT discontinuationAgonist therapyTreatment retentionIndependent predictorsHIV epidemicCost-effective HIV prevention strategyMethadone maintenance treatment patientsObservational longitudinal cohort studySpecialty addictions treatmentBuprenorphine maintenance treatmentHigh dosageHIV prevention strategiesLongitudinal cohort studyOpioid-dependent peopleTreatment discontinuationCohort studyMaintenance treatmentMale sexTreatment patientsPrevention strategiesDiscontinuationYounger ageCenter settingAddiction treatment
2019
Impact of Abstinence and of Reducing Illicit Drug Use Without Abstinence on Human Immunodeficiency Virus Viral Load
Nance RM, Trejo MEP, Whitney BM, Delaney JAC, Altice F, Beckwith CG, Chander G, Chandler R, Christopoulous K, Cunningham C, Cunningham WE, Del Rio C, Donovan D, Eron JJ, Fredericksen RJ, Kahana S, Kitahata MM, Kronmal R, Kuo I, Kurth A, Mathews WC, Mayer KH, Moore RD, Mugavero MJ, Ouellet LJ, Quan VM, Saag MS, Simoni JM, Springer S, Strand L, Taxman F, Young JD, Crane HM. Impact of Abstinence and of Reducing Illicit Drug Use Without Abstinence on Human Immunodeficiency Virus Viral Load. Clinical Infectious Diseases 2019, 70: 867-874. PMID: 30994900, PMCID: PMC7319266, DOI: 10.1093/cid/ciz299.Peer-Reviewed Original ResearchMeSH KeywordsHIVHIV InfectionsHumansIllicit DrugsLongitudinal StudiesSubstance-Related DisordersViral LoadConceptsMethamphetamine/crystalViral suppressionViral loadIllicit opioidsIllicit drug useDrug useRelative viral loadHuman immunodeficiency virus (HIV) viral loadNumber of PLWHSubstance useHIV viral loadHuman immunodeficiency virusLongitudinal cohort studyHarm reduction interventionsCrystal useCocaine/crackHIV clinicCohort studyVL suppressionImmunodeficiency virusImpact of abstinenceClinical studiesHigher oddsDrug categoriesOpioids
2018
Brief Report
Delaney JA, Nance RM, Whitney BM, Altice FL, Dong X, Trejo MEP, Matsuzaki M, Taxman FS, Chander G, Kuo I, Fredericksen R, Strand LN, Eron JJ, Geng E, Kitahata MM, Mathews WC, Mayer K, Moore RD, Saag MS, Springer S, Chandler R, Kahana S, Crane HM. Brief Report. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2018, 79: 283-287. PMID: 30036277, PMCID: PMC6681811, DOI: 10.1097/qai.0000000000001803.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overDepressionDrug UtilizationFemaleHIV InfectionsHumansIllicit DrugsLongitudinal StudiesMaleMiddle AgedYoung AdultConceptsPHQ-9 scoresDepressive symptomsSubstance useATS useLower oddsMean decreaseAmphetamine-type substancesAIDS Research NetworkCocaine/crack useDepressive symptom scoresMental health disordersJoint longitudinal-survival modelCocaine/crackPoor outcomeSymptom scoresPHQ-9Health disordersIllicit opiatesSymptomsPLWHLongitudinal assessmentSite cohortSubstance use frequencyCrack useAbstinenceA multisite, longitudinal study of risk factors for incarceration and impact on mental health and substance use among young transgender women in the USA
Hughto JMW, Reisner SL, Kershaw TS, Altice FL, Biello KB, Mimiaga MJ, Garofalo R, Kuhns LM, Pachankis JE. A multisite, longitudinal study of risk factors for incarceration and impact on mental health and substance use among young transgender women in the USA. Journal Of Public Health 2018, 41: 100-109. PMID: 29474682, PMCID: PMC6490767, DOI: 10.1093/pubmed/fdy031.Peer-Reviewed Original ResearchConceptsYoung transgender womenIllicit drug useRisk factorsTransgender womenRecent incarcerationDrug useSignificant independent predictorsIndividual risk factorsSubstance use disordersIndependent predictorsDepressive symptomsGeneral populationUse disordersMultilevel interventionsSomatic symptomsPoor healthRecent homelessnessMental healthStudy periodSubstance useWomenMixed effects modelsLongitudinal studySymptomsEffects model
2015
Sex-Related Disparities in Criminal Justice and HIV Treatment Outcomes: A Retrospective Cohort Study of HIV-Infected Inmates.
Meyer JP, Cepeda J, Taxman FS, Altice FL. Sex-Related Disparities in Criminal Justice and HIV Treatment Outcomes: A Retrospective Cohort Study of HIV-Infected Inmates. American Journal Of Public Health 2015, 105: 1901-10. PMID: 26180958, PMCID: PMC4529767, DOI: 10.2105/ajph.2015.302687.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyViral suppressionSex-related differencesHigh prevalenceRisk scoreHIV treatment outcomesRetrospective cohort studyHIV viral suppressionLarge contemporary cohortSex-related disparitiesSex-specific interventionsCommunity-based treatmentWomen's higher prevalenceLogistic regression modelsCJ populationsTreatable comorbiditiesCohort studyHIV outcomesContemporary cohortTreatment outcomesHIVCJ involvementIncarceration durationOlder ageSignificant correlatesPrevalence and Predictors of Mental/Emotional Distress Among HIV+ Jail Detainees at Enrollment in an Observational Study
Lincoln T, Simon-Levine D, Smith J, Donenberg GR, Springer SA, Zaller N, Altice FL, Moore K, Jordan AO, Draine J, Desabrais M. Prevalence and Predictors of Mental/Emotional Distress Among HIV+ Jail Detainees at Enrollment in an Observational Study. Journal Of Correctional Health Care 2015, 21: 125-139. PMID: 25788608, PMCID: PMC4433291, DOI: 10.1177/1078345815574566.Peer-Reviewed Original ResearchConceptsEmotional distressJail detaineesSeverity Index scoreAddiction Severity Index (ASI) scoresPoor physical healthMental health assessmentHIV/AIDSEmotional distress scoresObservational studyIndex scoreDistress scoresHealth servicesHealth RankingsSubstance abusePhysical healthJail systemHealth assessmentBisexual orientationSpecific correlatesDistressFamily supportPrevalenceScoresHigh levelsPLWHA
2013
Patterns of Homelessness and Implications for HIV Health After Release from Jail
Zelenev A, Marcus R, Kopelev A, Cruzado-Quinones J, Spaulding A, Desabrais M, Lincoln T, Altice FL. Patterns of Homelessness and Implications for HIV Health After Release from Jail. AIDS And Behavior 2013, 17: 181-194. PMID: 23657757, PMCID: PMC4625835, DOI: 10.1007/s10461-013-0472-6.Peer-Reviewed Original ResearchConceptsHIV treatment outcomesTreatment outcomesNon-homeless patientsDrug addiction severityUse of alcoholVirological suppressionHIV healthHealth behaviorsJail detaineesMental illnessSubstance abuseAddiction severityMental healthCorrelates of homelessnessIllicit drugsStable housingHousing statusEffects of housingOutcomesHealthDifferent patternsHIVLongitudinal dataPatientsIllnessIntegrating buprenorphine maintenance therapy into federally qualified health centers: Real-world substance abuse treatment outcomes
Haddad MS, Zelenev A, Altice FL. Integrating buprenorphine maintenance therapy into federally qualified health centers: Real-world substance abuse treatment outcomes. Drug And Alcohol Dependence 2013, 131: 127-135. PMID: 23332439, PMCID: PMC3674170, DOI: 10.1016/j.drugalcdep.2012.12.008.Peer-Reviewed Original ResearchConceptsQualified health centersSubstance abuse counselingHealth centersBuprenorphine maintenance treatment programCocaine useBuprenorphine maintenance therapyConcomitant cocaine useOpioid-dependent patientsMaintenance treatment programReal-world effectivenessSubstance abuse treatment outcomesElectronic health recordsHCV infectionMaintenance therapyPsychiatric comorbidityMean ageDependent patientsPsychiatric medicationsClinical trialsTreatment outcomesMood disordersFamily practitionersMore weeksTreatment programBMTFrequent Emergency Department Use Among Released Prisoners With Human Immunodeficiency Virus: Characterization Including a Novel Multimorbidity Index
Meyer JP, Qiu J, Chen NE, Larkin GL, Altice FL. Frequent Emergency Department Use Among Released Prisoners With Human Immunodeficiency Virus: Characterization Including a Novel Multimorbidity Index. Academic Emergency Medicine 2013, 20: 79-88. PMID: 23570481, PMCID: PMC3623800, DOI: 10.1111/acem.12054.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsComorbidityConfidence IntervalsEmergency Service, HospitalFemaleHealth Services MisuseHIV InfectionsHumansIncidenceLongitudinal StudiesMaleMiddle AgedMultivariate AnalysisOdds RatioPoisson DistributionPrisonersProspective StudiesRisk FactorsSeverity of Illness IndexSex FactorsSocioeconomic FactorsUnited StatesVulnerable PopulationsConceptsHuman immunodeficiency virusFrequent ED useFrequent ED usersFrequent emergency department (ED) useEmergency department useED useED usersMultimorbidity indexAntiretroviral therapyED visitsImmunodeficiency virusDischarge planningDepartment useWorse physical health-related qualityPhysical health-related qualityMultivariate Poisson regression modelChronic medical illnessLower physical HRQoLHealth-related qualityPoisson regression modelsPhysical HRQoLMedical illnessPsychiatric illnessPsychiatric correlatesIllness
2012
Emergency Department Use by Released Prisoners with HIV: An Observational Longitudinal Study
Meyer JP, Qiu J, Chen NE, Larkin GL, Altice FL. Emergency Department Use by Released Prisoners with HIV: An Observational Longitudinal Study. PLOS ONE 2012, 7: e42416. PMID: 22879972, PMCID: PMC3411742, DOI: 10.1371/journal.pone.0042416.Peer-Reviewed Original ResearchConceptsED useEmergency departmentHIV careED visitsSelf-administered antiretroviral therapyMultivariate modelContinuous HIV carePrimary HIV careEmergency department useAcute febrile syndromeObservational longitudinal studyAlcohol addiction severityED contactAntiretroviral therapyComorbid diseasesHIV severityPrimary outcomeFebrile syndromeSubstance use issuesDepartment useSevere depressionGreater social supportHealthcare resourcesMental illnessPoisson regressionRetention on buprenorphine treatment reduces emergency department utilization, but not hospitalization, among treatment-seeking patients with opioid dependence
Schwarz R, Zelenev A, Bruce RD, Altice FL. Retention on buprenorphine treatment reduces emergency department utilization, but not hospitalization, among treatment-seeking patients with opioid dependence. Journal Of Substance Use And Addiction Treatment 2012, 43: 451-457. PMID: 22534003, PMCID: PMC3419304, DOI: 10.1016/j.jsat.2012.03.008.Peer-Reviewed Original ResearchConceptsBuprenorphine maintenance treatmentHealthcare utilizationED utilizationEmergency department usageOpioid-dependent patientsEmergency department utilizationLate-stage diseaseTreatment-seeking patientsBuprenorphine treatmentChart reviewPerson yearsED useMaintenance treatmentOpioid dependenceDependent patientsPrimary careHospitalizationDrug usersNegative binomial regressionBinomial regressionPatientsComparison of timeTreatmentAverage lengthStay
2008
Clinical Outcomes of Hepatitis C Treatment in a Prison Setting: Feasibility and Effectiveness for Challenging Treatment Populations
Maru DS, Bruce RD, Basu S, Altice FL. Clinical Outcomes of Hepatitis C Treatment in a Prison Setting: Feasibility and Effectiveness for Challenging Treatment Populations. Clinical Infectious Diseases 2008, 47: 952-961. PMID: 18715156, PMCID: PMC4847716, DOI: 10.1086/591707.Peer-Reviewed Original ResearchConceptsSustained virological responseRate of prescriptionVirological responsePEG-RBVBaseline HCV RNA levelHepatic C virus infectionHCV genotype 1 infectionBaseline major depressionC virus infectionChronic HCV infectionHCV RNA levelsTreatment-naive patientsGenotype 1 infectionHepatitis C treatmentOutcome of treatmentUse of medicationsNewer mood stabilizersHCV infectionHIV infectionClinical outcomesMood stabilizersAntipsychotic medicationBlack raceClinical effectivenessMajor depression
2005
Attitudes toward and beliefs about prenatal HIV testing policies and mandatory HIV testing of newborns among drug users.
Fielder O, Altice FL. Attitudes toward and beliefs about prenatal HIV testing policies and mandatory HIV testing of newborns among drug users. AIDS & Public Policy Journal 2005, 20: 74-91. PMID: 17624031.Peer-Reviewed Original ResearchConceptsHIV testingLongitudinal cohort studyMandatory HIV testingPregnant womenDrug usersCohort studyMandatory testingCertain races/ethnicitiesPerinatal HIV testingPrior HIV testingHigh-risk womenHIV testing policiesHealthcare systemActive drug usersMajority of subjectsFocus groupsStructured interviewsRace/ethnicityRespondent-driven samplingHIV statusBaby's healthAdverse outcomesPrenatal careSuboptimal careHealth beliefs
1995
Women Living with Drug Abuse and HIV Disease: Drug Abuse Treatment Access and Secondary Prevention Issues
Weissman G, Melchior L, Huba G, Smereck G, Needle R, McCarthy S, Jones A, Genser S, Cottler L, Booth R, Altice F. Women Living with Drug Abuse and HIV Disease: Drug Abuse Treatment Access and Secondary Prevention Issues. Journal Of Psychoactive Drugs 1995, 27: 401-411. PMID: 8788695, DOI: 10.1080/02791072.1995.10471704.Peer-Reviewed Original ResearchConceptsHIV secondary preventionDrug abuse treatment servicesDrug abuse treatmentSecondary preventionTreatment servicesAbuse treatmentDrug abuseOutpatient drug-free treatmentSecondary prevention issuesDrug-free treatmentDrug abuse treatment systemFirst yearHIV diseaseInjection drugsService utilizationTreatment accessDrug abusersDrug usersTreatment availabilityPositive findingsOutpatient drug abuse treatmentHealth resourcesDrug detoxificationWomenPrevention issuesWomen living with substance abuse and HIV disease: medical care access issues.
Weissman G, Melchior L, Huba G, Altice F, Booth R, Cottler L, Genser S, Jones A, McCarthy S, Needle R. Women living with substance abuse and HIV disease: medical care access issues. Journal Of The American Medical Women's Association 1995, 50: 115-20. PMID: 7657944.Peer-Reviewed Original ResearchConceptsFirst positive HIV testHIV disease coursePositive HIV testHIV testing historyMedical servicesPost-test counselingMental health servicesDrug-using womenUse of healthHIV diseaseHIV testDisease courseDrug abusersTesting historyHealth servicesMen subjectsHealth resourcesSubstance abuseDrug abuseWomenMore womenFirst-year findingsServices AdministrationNational InstituteLongitudinal study