2020
Tocilizumab Treatment for Cytokine Release Syndrome in Hospitalized Patients With Coronavirus Disease 2019 Survival and Clinical Outcomes
Price CC, Altice FL, Shyr Y, Koff A, Pischel L, Goshua G, Azar MM, Mcmanus D, Chen SC, Gleeson SE, Britto CJ, Azmy V, Kaman K, Gaston DC, Davis M, Burrello T, Harris Z, Villanueva MS, Aoun-Barakat L, Kang I, Seropian S, Chupp G, Bucala R, Kaminski N, Lee AI, LoRusso PM, Topal JE, Dela Cruz C, Malinis M. Tocilizumab Treatment for Cytokine Release Syndrome in Hospitalized Patients With Coronavirus Disease 2019 Survival and Clinical Outcomes. CHEST Journal 2020, 158: 1397-1408. PMID: 32553536, PMCID: PMC7831876, DOI: 10.1016/j.chest.2020.06.006.Peer-Reviewed Original ResearchConceptsCytokine release syndromeTocilizumab-treated patientsSevere diseaseRelease syndromeTocilizumab treatmentInflammatory biomarkersNonsevere diseaseSoluble IL-2 receptor levelsHigh-sensitivity C-reactive proteinIL-2 receptor levelsConsecutive COVID-19 patientsIL-6 receptor antagonistMechanical ventilation outcomesC-reactive proteinCOVID-19 patientsHigher admission levelsRace/ethnicityMV daysVentilation outcomesAdverse eventsChart reviewClinical responseMedian ageWhite patientsClinical outcomes
2007
Pharmacological pain control for human immunodeficiency virus–infected adults with a history of drug dependence
Basu S, Bruce RD, Barry DT, Altice FL. Pharmacological pain control for human immunodeficiency virus–infected adults with a history of drug dependence. Journal Of Substance Use And Addiction Treatment 2007, 32: 399-409. PMID: 17481463, PMCID: PMC2128698, DOI: 10.1016/j.jsat.2006.10.005.Peer-Reviewed Original ResearchConceptsSubstance use disordersPharmacological pain controlChronic pain conditionsUse disordersPain controlPain conditionsHuman immunodeficiency virus-infected adultsAberrant drug-taking behaviorsHIV-specific issuesComplaints of painPain management servicesHuman immunodeficiency virusTreatment of painEvidence-based guidanceDrug-taking behaviorClinical reviewImmunodeficiency virusDrug interactionsPatientsDrug dependenceHIVPainDisordersCliniciansPhysicians