Global patterns of opioid use and dependence: harms to populations, interventions, and future action
Degenhardt L, Grebely J, Stone J, Hickman M, Vickerman P, Marshall BDL, Bruneau J, Altice FL, Henderson G, Rahimi-Movaghar A, Larney S. Global patterns of opioid use and dependence: harms to populations, interventions, and future action. The Lancet 2019, 394: 1560-1579. PMID: 31657732, PMCID: PMC7068135, DOI: 10.1016/s0140-6736(19)32229-9.Peer-Reviewed Original ResearchConceptsOpioid agonist treatmentOpioid useExtramedical opioid useIllicit opioid useRisk Factor StudyHepatitis C virusDrug-related harmRange of interventionsHIV mortalityOverall mortalityAgonist treatmentExtramedical usePatient acceptabilityC virusHigh prevalenceOpioid overdoseHigh-income countriesGlobal burdenOpioidsMultiple healthEffective interventionsInterventionTreatment qualityDrugsHIV