2010
Integrins stimulate E-cadherin-mediated intercellular adhesion by regulating Src-kinase activation and actomyosin contractility
Martinez-Rico C, Pincet F, Thiery JP, Dufour S. Integrins stimulate E-cadherin-mediated intercellular adhesion by regulating Src-kinase activation and actomyosin contractility. Journal Of Cell Science 2010, 123: 712-722. PMID: 20144995, DOI: 10.1242/jcs.047878.Peer-Reviewed Original ResearchConceptsIntercellular adhesionActomyosin contractilityCell doubletsE-cadherin-mediated intercellular adhesionIntercellular adhesion strengthSrc family kinasesCell-matrix interactionsSrc kinase activationExistence of crosstalkRole of integrinsFamily kinasesCadherin-7Cell plasticityMolecular crosstalkMajor adhesion moleculeIntegrin stimulationCell spreadingCadherinCell adhesionII activityIntegrinsPolylysine-coated beadsAdhesion moleculesCrosstalkAdhesion
2005
Prototypical Type I E-cadherin and Type II Cadherin-7 Mediate Very Distinct Adhesiveness through Their Extracellular Domains*
Chu YS, Eder O, Thomas WA, Simcha I, Pincet F, Ben-Ze'ev A, Perez E, Thiery JP, Dufour S. Prototypical Type I E-cadherin and Type II Cadherin-7 Mediate Very Distinct Adhesiveness through Their Extracellular Domains*. Journal Of Biological Chemistry 2005, 281: 2901-2910. PMID: 16253998, DOI: 10.1074/jbc.m506185200.Peer-Reviewed Original ResearchConceptsType II cadherinsE-cadherinIntercellular adhesivenessChimeric cadherinsTissue morphogenesisCadherin expression levelsCytoskeletal complexCytoplasmic tailCadherin-7Adherent junctionsCell doubletsCadherinExtracellular domainType ICell adhesivityExpression levelsStable complexesLow adhesivityCellsMorphogenesisAdhesivityComplexesProfound implicationsHigh adhesivityRegulation