2009
Force spectroscopy of a single artificial biomolecule bond: The Kramers’ high-barrier limit holds close to the critical force
Husson J, Dogterom M, Pincet F. Force spectroscopy of a single artificial biomolecule bond: The Kramers’ high-barrier limit holds close to the critical force. The Journal Of Chemical Physics 2009, 130: 051103. PMID: 19206951, DOI: 10.1063/1.3077010.Peer-Reviewed Original ResearchConceptsHigh-force regimeHigh barrier limitOptical tweezersEnergy barrierMicron-size beadsKramers approximationBarrier energyForce spectroscopyHigh energy barrierExponential decayEnergy profilesThermal energyEnergyApproximationTweezersBond studyCritical forceRecent modelsDecayKinetics of escapeSpectroscopyKramerRegimeBondsForce
2008
The Surface Force Apparatus to Reveal the Energetics of Biomolecules Assembly. Application to DNA Bases Pairing and SNARE Fusion Proteins Folding
Perez E, Li F, Tareste D, Pincet F. The Surface Force Apparatus to Reveal the Energetics of Biomolecules Assembly. Application to DNA Bases Pairing and SNARE Fusion Proteins Folding. Cellular And Molecular Bioengineering 2008, 1: 240. DOI: 10.1007/s12195-008-0025-7.Peer-Reviewed Original ResearchSNARE proteinsLipid bilayersMolecular binding energyIntracellular fusion eventsSurface force apparatusIntermediate assembly statesSNAREpin assemblyNanoscale resolutionBiomolecule assemblyForce apparatusSFA measurementsBiological moleculesBinding energiesLipid headgroupsFusion eventsMembrane fusionFusion proteinInteraction energyConformational changesAssembly stateAdhesion forceDNA basesProteinBilayersEnergy
2007
Energetics and dynamics of SNAREpin folding across lipid bilayers
Li F, Pincet F, Perez E, Eng WS, Melia TJ, Rothman JE, Tareste D. Energetics and dynamics of SNAREpin folding across lipid bilayers. Nature Structural & Molecular Biology 2007, 14: 890-896. PMID: 17906638, DOI: 10.1038/nsmb1310.Peer-Reviewed Original Research
2004
Can Small Complex Chains Be Treated as Polymers?
Gourier C, Pincet F, Le Bouar T, Zhang Y, Esnault J, Mallet J, Sinay P, Perez E. Can Small Complex Chains Be Treated as Polymers? Macromolecules 2004, 37: 8778-8784. DOI: 10.1021/ma035905m.Peer-Reviewed Original Research
1997
Quantitative Analysis of Holes in Supported Bilayers Providing the Adsorption Energy of Surfactants on Solid Substrate
Bassereau P, Pincet F. Quantitative Analysis of Holes in Supported Bilayers Providing the Adsorption Energy of Surfactants on Solid Substrate. Langmuir 1997, 13: 7003-7007. DOI: 10.1021/la970515c.Peer-Reviewed Original ResearchSecond monolayerFirst monolayerMode atomic force microscopy experimentsAtomic force microscopy experimentsForce microscopy experimentsMicroscopy experimentsHolesSupported bilayersDesorption of lipidRange 1Ratio measurementsAdsorption energyMonolayersEnergySolid surfaceBilayersSolid substrateMixed bilayersLow adsorption energyAmphiphilic moleculesQuantitative analysisMeasurementsSimple techniqueNew simple techniqueDOPC
1996
SPECIFIC FORCES BETWEEN DNA BASES
PINCET F, PEREZ E, BRYANT G, LEBEAU L, MIOSKOWSKI C. SPECIFIC FORCES BETWEEN DNA BASES. Modern Physics Letters B 1996, 10: 81-99. DOI: 10.1142/s0217984996000122.Peer-Reviewed Original ResearchSurface force apparatusChemical functional groupsNon-specific interactionsSpecific molecular interactionsForce apparatusMolecular recognitionH bondsFunctional groupsSize complementarityMolecular interactionsComplementary moleculesDNA basesSpecific interactionsAdhesion energyMoleculesNucleosidesSurfaceUnusual behaviorChemistrySize effectInteractionFluid characterSmall modificationsEnergyGood agreement