1993
Resetting of tubuloglomerular feedback by interrupting early distal flow
MORSING P, VELAZQUEZ H, ELLISON D, WRIGHT FS. Resetting of tubuloglomerular feedback by interrupting early distal flow. Acta Physiologica 1993, 148: 63-68. PMID: 8333296, DOI: 10.1111/j.1748-1716.1993.tb09532.x.Peer-Reviewed Original ResearchConceptsAfferent arteriolesMacula densaTGF mechanismDistal tubulesDistal nephronMacula densa segmentStop-flow pressureTubuloglomerular feedback mechanismHalf-maximal decreaseMacula densa plaqueDelta PsfGlomerular arteriolesTubuloglomerular feedbackDistal flowExtraglomerular mesangiumGlomerular dynamicsSame nephronTubular fluidTubular segmentsOrthograde microperfusionArteriolesNephronSignificant increaseBlockadeConcentration of sodium
1991
Adaptation of distal convoluted tubule of rats. II. Effects of chronic thiazide infusion
Morsing P, Velazquez H, Wright FS, Ellison DH. Adaptation of distal convoluted tubule of rats. II. Effects of chronic thiazide infusion. American Journal Of Physiology 1991, 261: f137-f143. PMID: 1858894, DOI: 10.1152/ajprenal.1991.261.1.f137.Peer-Reviewed Original ResearchConceptsDistal tubulesDistal tubule cellsTubule cellsThiazide-sensitive transportersFree-flow micropunctureVehicle-treated animalsDistal convoluted tubuleRenal cortical membranesReceptor binding studiesHigh-affinity receptorPmol/minIntrinsic transport capacityMammalian distal tubuleHCTZ groupChronic blockadeChronic administrationDirect functional measurementsCortical membranesConvoluted tubulesOsmotic pumpThiazide receptorCl deliveryTubule fluidApical membraneHydrochlorothiazide