1993
Renal mechanism of trimethoprim-induced hyperkalemia.
Velázquez H, Perazella MA, Wright FS, Ellison DH. Renal mechanism of trimethoprim-induced hyperkalemia. Annals Of Internal Medicine 1993, 119: 296-301. PMID: 8328738, DOI: 10.7326/0003-4819-119-4-199308150-00008.Peer-Reviewed Original ResearchConceptsRenal potassium excretionPotassium excretionMammalian distal nephronDistal tubulesTrimethoprim therapyPotassium secretionDistal nephronMale Sprague-Dawley ratsLumen-negative transepithelial voltageTransepithelial voltageNormal adrenocortical functionSeverity of hyperkalemiaTranstubular potassium gradientUrine electrolyte levelsSodium channelsRenal sodium excretionGlomerular filtration rateSerum potassium levelsSerum potassium concentrationNormal rat chowSprague-Dawley ratsRenal distal tubulesPotassium concentrationKidney distal tubuleMembrane sodium channels
1992
Luminal influences on potassium secretion: chloride, sodium, and thiazide diuretics
Velazquez H, Ellison DH, Wright FS. Luminal influences on potassium secretion: chloride, sodium, and thiazide diuretics. American Journal Of Physiology 1992, 262: f1076-f1082. PMID: 1621812, DOI: 10.1152/ajprenal.1992.262.6.f1076.Peer-Reviewed Original Research