A Dimeric Structure for Archaeal Box C/D Small Ribonucleoproteins
Bleichert F, Gagnon KT, Brown BA, Maxwell ES, Leschziner AE, Unger VM, Baserga SJ. A Dimeric Structure for Archaeal Box C/D Small Ribonucleoproteins. Science 2009, 325: 1384-1387. PMID: 19745151, PMCID: PMC2975540, DOI: 10.1126/science.1176099.Peer-Reviewed Original ResearchConceptsBox C/D sRNPArchaeal box C/D sRNPsRibosomal RNASingle-particle electron microscopyTarget ribosomal RNAArchaeon Methanocaldococcus jannaschiiOptimal protein synthesisRibose methylationMethanocaldococcus jannaschiiSmall ribonucleoproteinRNA componentEnzymatic functionSRNPDimeric structureMutational analysisProtein componentsProtein synthesisMethylationBase pairingRNAEukaryotesSnoRNPsArchaeaJannaschiiRibonucleoprotein