2021
Invasive thymoma – Which patients benefit from post-operative radiotherapy?
Muslim Z, Baig MZ, Weber JF, Detterbeck FC, Connery CP, Spera JA, Bhora FY. Invasive thymoma – Which patients benefit from post-operative radiotherapy? Asian Cardiovascular And Thoracic Annals 2021, 29: 935-942. PMID: 33975467, DOI: 10.1177/02184923211017094.Peer-Reviewed Original ResearchConceptsPost-operative radiotherapyWorld Health Organization histologyMasaoka-Koga stageStage III thymomaPropensity-matched cohortStage III diseaseClinical pathological factorsEnd Results (SEER) databasePositive prognostic indicatorUnderwent surgerySurgical treatmentThymoma patientsAdvanced thymomaB3 tumorsPrognostic implicationsResults databaseTumor sizeInvasive thymomaPrognostic indicatorSurvival differencesPatientsRadiotherapyThymomaSurgeryTumors
2013
Impact of preoperative radiation on survival of patients with T3N0 >7-cm non–small cell lung cancers treated with anatomic resection using the Surveillance, Epidemiology, and End Results database
Moreno AC, Morgensztern D, Yu JB, Boffa DJ, Decker RH, Detterbeck FC, Kim AW. Impact of preoperative radiation on survival of patients with T3N0 >7-cm non–small cell lung cancers treated with anatomic resection using the Surveillance, Epidemiology, and End Results database. Journal Of Surgical Research 2013, 184: 10-18. PMID: 23583079, DOI: 10.1016/j.jss.2013.03.053.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAgedAged, 80 and overCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellFemaleFollow-Up StudiesHumansIncidenceKaplan-Meier EstimateLung NeoplasmsMaleMiddle AgedMultivariate AnalysisNeoadjuvant TherapyPneumonectomyPreoperative CareProportional Hazards ModelsSEER ProgramYoung AdultConceptsNon-small cell lung cancerLung cancer-specific survivalEnd Results (SEER) databaseNeoadjuvant radiationSurvival of patientsCell lung cancerResults databaseLung cancerLarge non-small cell lung cancersFive-year overallCancer-specific survivalEffect of surgeryKaplan-Meier methodCox regression modelLog-rank testCombination of chemotherapyLong-term survivalAnatomic resectionPreoperative radiationWorse OSTherapeutic challengeLarge tumorsPneumonectomyLobectomyPatients
2006
Postoperative Radiotherapy for Stage II or III Non–Small-Cell Lung Cancer Using the Surveillance, Epidemiology, and End Results Database
Lally BE, Zelterman D, Colasanto JM, Haffty BG, Detterbeck FC, Wilson LD. Postoperative Radiotherapy for Stage II or III Non–Small-Cell Lung Cancer Using the Surveillance, Epidemiology, and End Results Database. Journal Of Clinical Oncology 2006, 24: 2998-3006. PMID: 16769986, DOI: 10.1200/jco.2005.04.6110.Peer-Reviewed Original ResearchConceptsT3-4 tumour stageUse of PORTN2 nodal diseaseEnd Results (SEER) databasePostoperative radiotherapyCell lung cancerLymph nodesNodal diseaseResults databaseTumor stageLung cancerNode stageStage IIHigher American Joint CommitteeAdvanced node stageAmerican Joint CommitteePopulation-based cohortLarger tumor sizeMedian followPerioperative mortalityMale sexTumor sizeSubset analysisCancer stageInclusion criteria