Stromal cell‐derived factor 1 (SDF‐1, CXCL12) is increased in subacromial bursitis and downregulated by steroid and nonsteroidal anti‐inflammatory agents
Kim Y, Bigliani LU, Fujisawa M, Murakami K, Chang S, Lee H, Lee FY, Blaine TA. Stromal cell‐derived factor 1 (SDF‐1, CXCL12) is increased in subacromial bursitis and downregulated by steroid and nonsteroidal anti‐inflammatory agents. Journal Of Orthopaedic Research® 2006, 24: 1756-1764. PMID: 16779827, DOI: 10.1002/jor.20197.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalBursa, SynovialBursitisCells, CulturedChemokine CXCL12Chemokines, CXCCyclooxygenase 2 InhibitorsDexamethasoneDown-RegulationEnzyme-Linked Immunosorbent AssayHumansIn Vitro TechniquesMiddle AgedOligonucleotide Array Sequence AnalysisReverse Transcriptase Polymerase Chain ReactionRNA, MessengerRotator CuffTendinopathyConceptsReal-time reverse transcription-polymerase chain reactionSDF-1 proteinEnzyme-linked immunosorbent assayCOX-2 inhibitorsStromal cell-derived factor-1Cell-derived factor-1SDF-1 expressionSubacromial bursaSDF-1Subacromial bursitisReal-time RT-PCRBursal cellsBursal tissueNormal bone marrow stromal cellsNonsteroidal anti-inflammatory agentsSDF-1 expression levelsAnti-inflammatory medicationsUse of steroidsAnti-inflammatory agentsFactor 1Reverse transcription-polymerase chain reactionSubacromial bursal tissueRotator cuff diseaseTranscription-polymerase chain reactionSubacromial bursa tissue