2019
Defining preoperative imaging findings of sacral chordomas associated with decreased overall survival and local recurrence
Munger AM, Geddes BJ, Lee FY. Defining preoperative imaging findings of sacral chordomas associated with decreased overall survival and local recurrence. Journal Of Spine Surgery 2019, 5: 171-173. PMID: 31032452, PMCID: PMC6465459, DOI: 10.21037/jss.2019.03.04.Peer-Reviewed Original Research
2018
Molecular Targeted Therapy Approach to Musculoskeletal Tumors
Ibe I, Haynes M, Koo A, Lindskog D, Friedlaender GE, Lee FY. Molecular Targeted Therapy Approach to Musculoskeletal Tumors. Techniques In Orthopaedics 2018, 33: 135-139. PMID: 36186916, PMCID: PMC9524233, DOI: 10.1097/bto.0000000000000298.Peer-Reviewed Original Research
2014
Tumor-Induced Osteomalacia Secondary to a Fibroblast Growth Factor 23-Secreting Phosphaturic Mesenchymal Tumor in the Foot
Kim Y, Stein E, Remotti F, Lee FY. Tumor-Induced Osteomalacia Secondary to a Fibroblast Growth Factor 23-Secreting Phosphaturic Mesenchymal Tumor in the Foot. JBJS Case Connector 2014, 4: e22. PMID: 29252581, DOI: 10.2106/jbjs.cc.l.00202.Peer-Reviewed Original Research
2012
Modern Interpretation of Giant Cell Tumor of Bone: Predominantly Osteoclastogenic Stromal Tumor
Kim Y, Nizami S, Goto H, Lee FY. Modern Interpretation of Giant Cell Tumor of Bone: Predominantly Osteoclastogenic Stromal Tumor. Clinics In Orthopedic Surgery 2012, 4: 107-116. PMID: 22662295, PMCID: PMC3360182, DOI: 10.4055/cios.2012.4.2.107.Peer-Reviewed Original ResearchConceptsGiant cell tumorStromal cell-derived factor-1Tumor necrosis factorCell tumorsBone destructionNuclear factor kappa-B ligandCell-derived factor-1Stromal cell tumorsPro-osteoclastogenic cytokinesGCT treatmentAdjuvant therapySurgical excisionStromal tumorsTumor comprisingInflammatory cytokinesChemoattractant proteinNecrosis factorParacrine loopExcessive osteoclastogenesisReceptor activatorOrthopaedic surgeonsOsteoclast precursorsOsteoclastic cellsMesenchymal originTumors
2010
Surmounting Chemotherapy and Radioresistance in Chondrosarcoma: Molecular Mechanisms and Therapeutic Targets
Onishi AC, Hincker AM, Lee FY. Surmounting Chemotherapy and Radioresistance in Chondrosarcoma: Molecular Mechanisms and Therapeutic Targets. Sarcoma 2010, 2011: 381564. PMID: 21234363, PMCID: PMC3018623, DOI: 10.1155/2011/381564.Peer-Reviewed Original ResearchNature of chemotherapyNew molecular targetsDirected therapyPrimary malignancySurgical resectionRadiation regimensCurative treatmentMolecular mechanismsSuccessful treatmentTherapeutic targetChemotherapyChondrosarcomaMolecular targetsTumorsTherapy researchTreatmentCurrent hypothesesResectionRegimensPatientsMalignancyTherapyDiagnosis
2004
Bisphosphonates May Reduce Recurrence in Giant Cell Tumor by Inducing Apoptosis
Chang SS, Suratwala SJ, Jung KM, Doppelt JD, Zhang HZ, Blaine TA, Kim TW, Winchester RJ, Lee FY. Bisphosphonates May Reduce Recurrence in Giant Cell Tumor by Inducing Apoptosis. Clinical Orthopaedics And Related Research® 2004, 426: 103-109. PMID: 15346059, DOI: 10.1097/01.blo.0000141372.54456.80.Peer-Reviewed Original ResearchConceptsGiant cell tumorCell tumorsAdjuvant therapyGiant cellsExogenous receptor activatorSpecific adjuvant therapyExtensive bone destructionTumor culturesLocal adjuvant therapyHigh recurrence rateNovel adjuvant therapyOsteoclastlike giant cellsNovel therapeutic agentsNF-kappaB ligandDose-dependent mannerBone destructionRecurrence rateAggressive tumorsBone resorptionSystemic useReceptor activatorAutocrine loopAutocrine mannerTumorsAutocrine regulation
1998
Reconstruction Of The Shoulder Joint Using An Acetabular Allograft
Lee FY, Hornicek FJ, Hazan EJ, Kloen P, Wolfe MA, Mankin HJ. Reconstruction Of The Shoulder Joint Using An Acetabular Allograft. Clinical Orthopaedics And Related Research® 1998, 357: 120-121. PMID: 9917707, DOI: 10.1097/00003086-199812000-00015.Peer-Reviewed Original ResearchConceptsShoulder jointAcetabular allograftWide resectionMusculoskeletal Tumor Society systemStable shoulder jointAggressive lesionsOsteoarticular allograftsAggressive tumorsCosmetic resultsFunctional resultsSurgical reconstructionAllograftsSecure reattachmentPatientsSoft tissueResectionCenter of motionSelect groupScapulaTumorsGlenoid regionJointsLesions