Interleukin-7 receptor expression and activation in nonhaematopoietic neoplastic cell lines
Cosenza L, Gorgun G, Urbano A, Foss F. Interleukin-7 receptor expression and activation in nonhaematopoietic neoplastic cell lines. Cellular Signalling 2002, 14: 317-325. PMID: 11858939, DOI: 10.1016/s0898-6568(01)00245-5.Peer-Reviewed Original ResearchMeSH KeywordsBrain NeoplasmsCell LineEpithelial CellsHematopoietic Stem CellsHumansImmunoblottingInterleukin Receptor Common gamma SubunitJanus Kinase 3Lung NeoplasmsNeoplasmsNuclease Protection AssaysProtein-Tyrosine KinasesProto-Oncogene ProteinsProto-Oncogene Proteins c-fynReceptors, Interleukin-7RNA, MessengerSignal TransductionTissue DistributionTranscription, GeneticTumor Cells, CulturedConceptsIL-7R mRNABrain tumor cell linesIL-7RIL-7RalphaCell linesTumor cell linesInterleukin-7 receptor expressionReceptor-directed therapyNational Cancer Institute tumor panelBreast cancer cell linesReceptor gamma chainLung cancer cellsInterleukin-2 receptor gamma chainHeterodimeric complex consistingS1 nuclease protection assaysCellular differentiation processesEpithelial tumor cellsCancer cell linesNuclease protection assaysS1 nuclease protectionLung cancerSerine residue phosphorylationReceptor expressionNeoplastic cell linesInterleukin-7STRUCTURE FUNCTION ANALYSIS OF INTERLEUKIN 7: REQUIREMENT FOR AN AROMATIC RING AT POSITION 143 OF HELIX D
vanderSpek JC, Sutherland JA, Gill BM, Gorgun G, Foss FM, Murphy JR. STRUCTURE FUNCTION ANALYSIS OF INTERLEUKIN 7: REQUIREMENT FOR AN AROMATIC RING AT POSITION 143 OF HELIX D. Cytokine 2002, 17: 227-233. PMID: 12027403, DOI: 10.1006/cyto.2002.1004.Peer-Reviewed Original ResearchAnimalsBinding, CompetitiveCell LineDose-Response Relationship, DrugElectrophoresis, Polyacrylamide GelEscherichia coliHistidineHumansInhibitory Concentration 50Interleukin-7MiceMutagenesis, Site-DirectedMutationPhenylalaninePlasmidsProlineProtein BindingProtein Structure, TertiaryReceptors, Interleukin-7Signal TransductionTryptophanTyrosine