2015
Genomic landscape of cutaneous T cell lymphoma
Choi J, Goh G, Walradt T, Hong BS, Bunick CG, Chen K, Bjornson RD, Maman Y, Wang T, Tordoff J, Carlson K, Overton JD, Liu KJ, Lewis JM, Devine L, Barbarotta L, Foss FM, Subtil A, Vonderheid EC, Edelson RL, Schatz DG, Boggon TJ, Girardi M, Lifton RP. Genomic landscape of cutaneous T cell lymphoma. Nature Genetics 2015, 47: 1011-1019. PMID: 26192916, PMCID: PMC4552614, DOI: 10.1038/ng.3356.Peer-Reviewed Original Research
2002
Mechanisms of apoptosis by the tyrphostin AG957 in hematopoietic cells
Urbano A, Gorgun G, Foss F. Mechanisms of apoptosis by the tyrphostin AG957 in hematopoietic cells. Biochemical Pharmacology 2002, 63: 689-692. PMID: 11992636, DOI: 10.1016/s0006-2952(01)00916-9.Peer-Reviewed Original ResearchConceptsCytochrome c/ApafPhosphatidylinositol-3-kinase/AktHematopoietic cellsTyrphostin tyrosine kinase inhibitorKinase/AktChronic myelogenous leukemia blastsMechanism of apoptosisCell line NALM-6BAD complexLeukemia cellsPhosphorylation stateC-CblAdaptor moleculeGrowth arrestAltered phosphorylationChronic myelogenous leukemia cellsMyelogenous leukemia cellsProgenitor cellsApoptosisTyrphostin AG957AG957NALM-6Kinase inhibitorsGrowth inhibitionAkt