2024
What N Is N-ough for MRI-Based Animal Neuroimaging?
Grandjean J, Lake E, Pagani M, Mandino F. What N Is N-ough for MRI-Based Animal Neuroimaging? ENeuro 2024, 11: eneuro.0531-23.2024. PMID: 38499355, PMCID: PMC10950324, DOI: 10.1523/eneuro.0531-23.2024.Peer-Reviewed Original ResearchMultimodal measures of spontaneous brain activity reveal both common and divergent patterns of cortical functional organization
Vafaii H, Mandino F, Desrosiers-Grégoire G, O’Connor D, Markicevic M, Shen X, Ge X, Herman P, Hyder F, Papademetris X, Chakravarty M, Crair M, Constable R, Lake E, Pessoa L. Multimodal measures of spontaneous brain activity reveal both common and divergent patterns of cortical functional organization. Nature Communications 2024, 15: 229. PMID: 38172111, PMCID: PMC10764905, DOI: 10.1038/s41467-023-44363-z.Peer-Reviewed Original Research
2023
SMC5 Plays Independent Roles in Congenital Heart Disease and Neurodevelopmental Disability
O'Brien M, Pryzhkova M, Lake E, Mandino F, Shen X, Karnik R, Atkins A, Xu M, Ji W, Konstantino M, Brueckner M, Ment L, Khokha M, Jordan P. SMC5 Plays Independent Roles in Congenital Heart Disease and Neurodevelopmental Disability. International Journal Of Molecular Sciences 2023, 25: 430. PMID: 38203602, PMCID: PMC10779392, DOI: 10.3390/ijms25010430.Peer-Reviewed Original Research
2022
The lateral entorhinal cortex is a hub for local and global dysfunction in early Alzheimer’s disease states
Mandino F, Yeow LY, Bi R, Sejin L, Bae HG, Baek SH, Lee CY, Mohammad H, Horien C, Teoh CL, Lee JH, Lai MK, Jung S, Fu Y, Olivo M, Gigg J, Grandjean J. The lateral entorhinal cortex is a hub for local and global dysfunction in early Alzheimer’s disease states. Cerebrovascular And Brain Metabolism Reviews 2022, 42: 1616-1631. PMID: 35466772, PMCID: PMC9441719, DOI: 10.1177/0271678x221082016.Peer-Reviewed Original ResearchConceptsAlzheimer's diseaseEntorhinal cortexFunctional connectivity lossEarly AD stagesEarly Alzheimer's diseaseLateral entorhinal cortexVentral networkSynaptic hyperexcitabilityAD progressionGlobal dysfunctionMouse modelOptogenetic activationProjection targetsPathophysiological modelAD stagesMice showNetwork alterationsActive phenotypeNeuronal facilitationEarly hallmarkDiseaseActivity alterationsFMRI signalsNeuronal underpinningsTauopathies
2021
A triple-network organization for the mouse brain
Mandino F, Vrooman R, Foo H, Yeow L, Bolton T, Salvan P, Teoh C, Lee C, Beauchamp A, Luo S, Bi R, Zhang J, Lim G, Low N, Sallet J, Gigg J, Lerch J, Mars R, Olivo M, Fu Y, Grandjean J. A triple-network organization for the mouse brain. Molecular Psychiatry 2021, 27: 865-872. PMID: 34650202, PMCID: PMC9054663, DOI: 10.1038/s41380-021-01298-5.Peer-Reviewed Original Research
2019
Functionalised iron oxide nanoparticles for multimodal optoacoustic and magnetic resonance imaging
Bell G, Balasundaram G, Attia A, Mandino F, Olivo M, Parkin I. Functionalised iron oxide nanoparticles for multimodal optoacoustic and magnetic resonance imaging. Journal Of Materials Chemistry B 2019, 7: 2212-2219. PMID: 32073580, DOI: 10.1039/c8tb02299b.Peer-Reviewed Original ResearchConceptsIron oxide nanoparticlesIron oxide coreOxide nanoparticlesOxide coreFacile synthesisRelaxivity coefficientCoordination chemistryNear-IR wavelengthsDye modificationDye attachmentNanoparticlesMultispectral optoacoustic tomography (MSOT) imagingOA analysisMRI contrastEndogenous contrastIR wavelengthsFlammaSynthesisWavelengthLiterature valuesOptoacousticsChemistryDyeProbeMultimodal characteristics